Bactericidal mode of action of plantaricin C
| Autor: | Wil N. Konings, Edmund R.S. Kunji, Arnold J. M. Driessen, Beatriz González, Juan E. Suárez, Erwin Glaasker |
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| Přispěvatelé: | Groningen Biomolecular Sciences and Biotechnology, Molecular Microbiology |
| Rok vydání: | 1996 |
| Předmět: |
Biology
PEP-5 Applied Microbiology and Biotechnology VESICLES FORCE chemistry.chemical_compound AUTOLYSIS Bacteriocin medicine Mode of action Nisin chemistry.chemical_classification Ecology Chemiosmosis INDUCTION food and beverages ARTIFICIAL MEMBRANES STREPTOCOCCUS-CREMORIS TRANSPORT Transmembrane protein NISIN Amino acid VOLTAGE-DEPENDENT DEPOLARIZATION chemistry Biochemistry Mechanism of action bacteria Efflux medicine.symptom Research Article Food Science Biotechnology |
| Zdroj: | Applied and environmental microbiology, 62(8), 2701-2709. AMER SOC MICROBIOLOGY |
| ISSN: | 1098-5336 0099-2240 |
| DOI: | 10.1128/aem.62.8.2701-2709.1996 |
| Popis: | Plantaricin C is a bacteriocin produced by Lactobacillus plantarum LL441 that kills sensitive cells by acting on the cytoplasmic membrane. In contrast to its lack of impact on immune cells, plantaricin C dissipates the proton motive force and inhibits amino acid transport in sensitive cells. In proteoliposomes, plantaricin C dissipates the transmembrane electrical potential, and in liposomes, it elicits efflux of entrapped carboxy-fluorescein. It is concluded that plantaricin C is a pore-forming bacteriocin that functions in a voltage-independent manner and does not require a specific protein receptor in the target membrane. |
| Databáze: | OpenAIRE |
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