Granulocyte colony formation in chronic granulocytic leukemia during stable, accelerated and blastic disease
| Autor: | C. A. Rhodes, Maureen A. Entringer, William A. Robinson |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
Chronic granulocytic leukemia
Disease Granulocyte Biology Prognosis General Biochemistry Genetics and Molecular Biology Peripheral blood Clone Cells Leukemia Myeloid Acute medicine.anatomical_structure Colony formation Bone Marrow Leukemia Myeloid Immunology medicine Leukocytes Humans Stable phase Bone marrow Cell Division Granulocytes |
| Zdroj: | Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 157(3) |
| ISSN: | 0037-9727 |
| Popis: | SummaryThe number of granulocyte colony forming cells (CFU-C) has been determined in the peripheral blood and bone marrow of patients with chronic granulocytic leukemia (CGL) during the stable, accelerated and blastic phases of the disease. These studies have corroborated previous work indicating that blood CFU-C numbers are high during the stable phase of CGL. In the accelerated and blast phases of CGL, CFU-C numbers in the peripheral blood and bone marrow may be decreased, normal or increased, but are not consistently low. Changes in CFU-C numbers could not be correlated with clinical patterns of CGL, or eventual outcome of the disease. |
| Databáze: | OpenAIRE |
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