IMMUNOLOGICAL PROFILE OF PATIENTS WITH OVARIAN-CANCER UNDER IMMUNOSTIMULATION WITH MURINE MONOCLONAL-ANTIBODIES

Autor:	Gustav Hör, Rp Baum, J.B. Oltrogge, B. Donnerstag, A Niesen, M Skierlo, L Trager
Rok vydání:	1995
Předmět:	Cancer Research Oncogene medicine.drug_class medicine.medical_treatment Cancer Immunotherapy Disease Biology medicine.disease Monoclonal antibody Molecular medicine Immune system Oncology Immunology medicine Ovarian cancer
Zdroj:	International Journal of Oncology.
ISSN:	1791-2423 1019-6439
DOI:	10.3892/ijo.6.4.853
Popis:	The longer survival of ovarian cancer patients after immunostimulation has been connected with the induction of an anti-tumor activity triggered by cellular and humoral immune responses. Our interest was to study the long-term influence on the immune system in relation to the various levels of the HAMA response and the disease stage. The immunological profile was evaluated by regularly performing phenotyping and functional analysis of peripheral blood lymphocytes (PBL). We report the statistical analysis of immunological data obtained in a study with 77 ovarian cancer patients examined over a period of up to 28 months. The results demonstrate that these immunological data are important for monitoring cancer patients under immunotherapy whereas they provide no prognostic significance.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4ce30d3e023c73419d249ce466e55a5 https://doi.org/10.3892/ijo.6.4.853 Zobrazit plný text záznamu