Effect of surface roughness on initial responses of osteoblast-like cells on two types of zirconia
| Autor: | Motoharu Miyamoto, Seiji Ban, Miho Machigashira, Hironobu Takeuchi, Kazuyuki Noguchi, Daisuke Yamashita, Yuichi Izumi |
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| Rok vydání: | 2009 |
| Předmět: |
Materials science
Surface Properties Oxide chemistry.chemical_element Integrin alpha5 engineering.material Actin cytoskeleton organization chemistry.chemical_compound Mice Materials Testing medicine Surface roughness Aluminum Oxide Cell Adhesion Animals Cubic zirconia Yttrium Composite material General Dentistry Titanium Nanocomposite Osteoblasts Integrin beta1 Diamond Osteoblast 3T3 Cells Cerium Flow Cytometry Dental Porcelain Actin Cytoskeleton medicine.anatomical_structure chemistry Ceramics and Composites engineering Zirconium |
| Zdroj: | Dental materials journal. 28(4) |
| ISSN: | 0287-4547 |
| Popis: | The aim of this study was to evaluate the effect of surface roughness on the initial attachment of mouse osteoblast-like cells on ceriastabilized zirconia/alumina nanocomposite (NANOZR) and yttria-stabilized zirconia (3Y-TZP) in comparison to those on pure titanium (Ti) and alumina oxide (AO). Specimens with smooth and rough surfaces were prepared by grinding with diamond paper or by sandblasting, respectively. For four substrates examined, the number of attached cells on the rough surface specimens was significantly higher than that on the smooth surface specimens (p < 0.05). Integrin alpha(5) and beta(1) expression had a greater increase in rough surface specimens than in smooth surface specimens. Actin cytoskeleton organization was, however, similar for both smooth and rough surface specimens. NANOZR and 3Y-TZP produced good cell attachment, similar to Ti and AO. The overall results demonstrated that NANOZR and 3Y-TZP with rough surface could provide good initial cell responses, adequate for future implant usage. |
| Databáze: | OpenAIRE |
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