Age-related macular degeneration: is polypoidal choroidal vasculopathy recognized and treated?

Autor: David R. Chow, Peter J. Kertes, Fil Altomare, David T. Wong, Michael H. Brent, Alan R. Berger, Yufeng N. Chen, Robert G. Devenyi, Kenneth T. Eng, Patrick Yoo, Carol Schwartz, Wai Ching Lam, Alexander K. Soon, Radha P. Kohly, Louis R. Giavedoni, Rajeev H. Muni
Rok vydání: 2017
Předmět:
Indocyanine Green
Male
Canada
China
medicine.medical_specialty
Visual acuity
genetic structures
Visual Acuity
Angiogenesis Inhibitors
complex mixtures
White People
Macular Degeneration
03 medical and health sciences
chemistry.chemical_compound
Polyps
0302 clinical medicine
Asian People
Internal medicine
Age related
Ophthalmology
medicine
Humans
030212 general & internal medicine
Fluorescein Angiography
Coloring Agents
Aged
Retrospective Studies
Aged
80 and over
medicine.diagnostic_test
business.industry
Retrospective cohort study
General Medicine
Macular degeneration
medicine.disease
Fluorescein angiography
University hospital
Combined Modality Therapy
Choroidal Neovascularization
eye diseases
Choroidal neovascularization
Photochemotherapy
chemistry
030221 ophthalmology & optometry
Female
sense organs
medicine.symptom
business
Indocyanine green
Zdroj: Canadian Journal of Ophthalmology. 52:475-479
ISSN: 0008-4182
DOI: 10.1016/j.jcjo.2017.02.014
Popis: Objective To assess how polypoidal choroidal vasculopathy (PCV) is recognized and treated, and to assess whether treatment outcomes are different between Chinese and Caucasian Canadian patients with age-related macular degeneration (AMD). Design Retrospective chart review. Participants 154 eyes from 135 Chinese patients and 2291 eyes from 1792 Caucasian patients who were newly diagnosed with either AMD or PCV and had more than 1 year of follow-up were included. Methods All newly diagnosed AMD patients presenting to the Retina Service of 3 Toronto University Hospitals, between March 25, 2008, to September 30, 2014, were reviewed. Results 10/154 eyes (6.5%) in Chinese Canadians and 16/2291 eyes (0.7%) in Caucasian Canadians were diagnosed as having PCV. Indocyanine green angiography (ICGA) was used to diagnose PCV in 20% of Chinese Canadians and 8.8% of Caucasian Canadians. Clinical practices with a larger percentage of Chinese patients were more likely to diagnose PCV in both Chinese ( p = 0.004) and Caucasian patients ( p = 0.03), were more likely to use photodynamic therapy (PDT) ( p p Conclusion Our study has shown that PCV is under-recognized in a Canadian population, and ICGA is underutilized. In clinical practices with a greater portion of Chinese patients, PCV is more often recognized and PDT is used more liberally.
Databáze: OpenAIRE
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