Acid hydrolases in blister fluid
| Autor: | Gunnar Volden |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
chemistry.chemical_classification
integumentary system biology Epidermis (botany) Phosphatase Acid phosphatase Exudates and Transudates Dermatology Tartrate Aminopeptidases Cathepsins Suction blister chemistry.chemical_compound Blister Enzyme chemistry Biochemistry Interstitial fluid biology.protein Biophysics Humans Extracellular Space skin and connective tissue diseases Fluoride Peptide Hydrolases |
| Zdroj: | British Journal of Dermatology. 99:49-52 |
| ISSN: | 1365-2133 0007-0963 |
| DOI: | 10.1111/j.1365-2133.1978.tb01960.x |
| Popis: | SUMMARY Acid phosphatase has been characterized and quantified in human suction blister fluid, interstitial fluid and serum. The acid phosphatases of suction blister fluid and scrum showed differences in their pH activity curves, Michaelis-Menton constants, heat stabilities and sensitivities to inhibition by tartrate and fluoride. The behaviour of the interstitial fluid enzyme was intermediate between these two. The levels of activity in blister fluid and serum were very similar, both being more than twice that of interstitial fluid. These results suggest that the acid phosphatase activity in suction blister fluid is derived largely from the overlying epidermis rather than from serum. |
| Databáze: | OpenAIRE |
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