Post-treatment skin reactions reported by cancer patients differ by race, not by treatment or expectations
| Autor: | Christopher W. Bole, Gary R. Morrow, Alice P. Pentland, Jane T. Hickok, Julie L. Ryan, R. C. Khanna, Lauren K. Colman, Colmar Figueroa-Moseley |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Male
Cancer Research medicine.medical_specialty medicine.medical_treatment skin reactions Pain Antineoplastic Agents Skin Diseases White People 03 medical and health sciences 0302 clinical medicine Neoplasms Surveys and Questionnaires Internal medicine Clinical Studies medicine Humans 030212 general & internal medicine race Chemotherapy Radiotherapy treatment integumentary system Symptom management business.industry Significant difference Cancer Middle Aged self-report medicine.disease 3. Good health Surgery Black or African American Radiation therapy Skin reaction Oncology 030220 oncology & carcinogenesis Female Drug Eruptions Radiodermatitis Skin cancer Post treatment business expectations |
| Zdroj: | British Journal of Cancer |
| ISSN: | 1532-1827 0007-0920 |
| DOI: | 10.1038/sj.bjc.6603842 |
| Popis: | Cancer patients may experience skin problems while undergoing chemotherapy and radiation therapy. Frequency of skin reactions may be influenced by skin pigmentation and psychological factors. A Symptom Inventory completed by 656 cancer patients nationwide before and after chemotherapy, radiation therapy, or chemotherapy plus radiation therapy was analysed to determine if treatment type, race (Black vs White), and pretreatment expectations influenced post-treatment skin reactions. Subsequent analysis of a local Symptom Inventory completed weekly for 5 weeks by 308 patients receiving radiation therapy examined severity of reported skin reactions. Significantly more patients receiving radiation therapy had stronger expectations of skin problems (62%) than patients receiving chemotherapy (40%, P=0.001) or chemotherapy plus radiation therapy (45%, P=0.003). Overall, expectations did not correlate with patient reported post-treatment skin problems in white (r=0.014, P=0.781) or black (r=0.021, P=0.936) patients. Although no significant difference was found between black and white patients in their pretreatment expectations of skin problems (P=0.32), black patients (10 out of 18, 56%) reported more skin problems than white patients (90 out of 393, 23%, P=0.001). Similarly, the local study showed that significantly more black patients (1 out of 5, 20%) reported severe skin reactions at the treatment site than white patients (12 out of 161, 8%). A direct correlation was observed between severity of skin problems and pain at the treatment site (r=0.541, P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|