Pattern of thermal damage and tissue carbonisation from endovenous radiofrequency ablation catheter – Using an in vitro porcine liver model
| Autor: | Charlotte E Davies, Emma B Dabbs, Olivia H Bishop, Max I. Riley, Mark S Whiteley |
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| Rok vydání: | 2020 |
| Předmět: |
Catheters
Swine medicine.medical_treatment 030204 cardiovascular system & hematology Varicose Veins 03 medical and health sciences 0302 clinical medicine Porcine liver Varicose veins Animals Medicine Saphenous Vein Vein business.industry General Medicine Ablation Radiofrequency ablation catheter Treatment Outcome medicine.anatomical_structure Liver Catheter Ablation Thermal damage medicine.symptom Cardiology and Cardiovascular Medicine business Nuclear medicine 030217 neurology & neurosurgery |
| Zdroj: | Phlebology: The Journal of Venous Disease. 36:489-495 |
| ISSN: | 1758-1125 0268-3555 |
| DOI: | 10.1177/0268355520975539 |
| Popis: | Background Successful endovenous thermoablation relies on transmural vein wall ablation. We investigated the pattern of thermal spread and tissue carbonisation from RadioFrequency-induced ThermoTherapy (RFiTT) at different powers and pull back methods, using a porcine liver model. Methods We used a previously validated in-vitro porcine liver model. Different powers from 5–25 W were used to administer 150 J. We compared continuous and pulsed energy delivery. Length, lateral spread, and total area of thermal damage, together with any tissue carbonisation, was measured using digital analysis software. Results All experiments used 150 J total energy. Total thermal damage area was smaller with lower power and pulsed energy. Continuous energy caused more tissue carbonisation than pulsed except at 25 W. Conclusion Reduced thermal damage with lower power or pulsed energy results from cooling due to increased time of treatment. Increasing the power increases tissue carbonisation. Optimal treatment is determined by the highest power used continuously that does not cause tissue carbonisation. |
| Databáze: | OpenAIRE |
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