Luteal phase support after mild ovulation induction with intrauterine insemination: an on-going debate

Autor:	Esra Bulgan Kilicdag, Tayfun Çok, Pinar Caglar Aytac, Bulent Haydardedeoglu, Gonca Çoban, Erhan Simsek
Rok vydání:	2016
Předmět:	Adult medicine.medical_specialty Endocrinology Diabetes and Metabolism medicine.medical_treatment 030209 endocrinology & metabolism Luteal Phase Luteal phase Insemination Young Adult 03 medical and health sciences 0302 clinical medicine Endocrinology Ovulation Induction Pregnancy medicine Humans In patient Insemination Artificial Progesterone Retrospective Studies Unexplained infertility Gynecology 030219 obstetrics & reproductive medicine Intrauterine insemination business.industry Obstetrics and Gynecology Administration Intravaginal Pregnancy rate Vaginal Creams Foams and Jellies Female lipids (amino acids peptides and proteins) Ovulation induction business Live birth Infertility Female Gonadotropins Polycystic Ovary Syndrome
Zdroj:	Gynecological Endocrinology. 32:543-547
ISSN:	1473-0766 0951-3590
Popis:	To evaluate the effect of luteal phase support (LPS) using progesterone vaginal gel on pregnancy rate (PR) and live birth rate (LBR) during cycles in which controlled ovarian stimulation (COH) was performed using gonadotropins with intrauterine insemination (IUI) cycles in patients with unexplained infertility and polycystic ovarian syndrome.From 2010 to 2015, all IUI cycles in which COH was performed using gonadotropins were evaluated retrospectively. LPS was not used until July 2013, after which vaginal progesterone gel was applied in the luteal phase of IUI cycles. Both groups of patients were evaluated in terms of the effect of LPS on PR and LBR.In total, 1578 IUI cycles were evaluated, of which 481 were LPS (+) and 1097 LPS (-). PR and LBR per cycle were 10.6% and 7.4%, respectively, in the LPS (+) group, and 11.6% and 7.7%, respectively, in the LPS (-) group (p = 0.31 and p = 0.25). PR and LBR per patient were 17% and 12%, respectively, in the LPS (+) group, and 17.4% and 12.3%, respectively, in the LPS (-) group (p = 0.48 and p = 0.82).We found no difference in PR and LBR per cycle and per patient according to the use of LPS in IUI cycles in which COH was performed using gonadotropins. Thus, routine use of LPS in gonadotropin-stimulated cycles requires further research involving larger numbers of patients.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b00438a30c42a369b62dc158e7b063 https://doi.org/10.3109/09513590.2016.1138460 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.