miRNAFold: a web server for fast miRNA precursor prediction in genomes

Autor: Fariza Tahi, Sébastien Tempel, Christophe Tav, Laurent Poligny
Přispěvatelé: Laboratoire de chimie bactérienne (LCB), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Institut de Microbiologie de la Méditerranée (IMM), Informatique, Biologie Intégrative et Systèmes Complexes (IBISC), Université d'Évry-Val-d'Essonne (UEVE), UEVE Council of Essonne Region
Jazyk: angličtina
Rok vydání: 2016
Předmět:
0301 basic medicine
Web server
RNA Folding
Interface (Java)
CLASSIFICATION
SEQUENCES
TOOL
Information Storage and Retrieval
Computational biology
[SDV.BC]Life Sciences [q-bio]/Cellular Biology
Biology
computer.software_genre
Bioinformatics
Genome
Computer graphics
03 medical and health sciences
Software
microRNA
Genetics
Computer Graphics
RNA Precursors
Web Server issue
Animals
Humans
[SDV.BBM]Life Sciences [q-bio]/Biochemistry
Molecular Biology
Internet
[SDV.GEN]Life Sciences [q-bio]/Genetics
business.industry
Sequence Analysis
RNA
Plants
[SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology
Identification (information)
MicroRNAs
030104 developmental biology
[SDE]Environmental Sciences
[SDV.IMM]Life Sciences [q-bio]/Immunology
The Internet
business
computer
Algorithms
Zdroj: Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2016, 44 (W1), pp.W181--W184. ⟨10.1093/nar/gkw459⟩
Nucleic Acids Research W1 (44), W181-W184. (2016)
Nucleic Acids Research, 2016, 44 (W1), pp.W181--W184. ⟨10.1093/nar/gkw459⟩
ISSN: 0305-1048
1362-4962
DOI: 10.1093/nar/gkw459⟩
Popis: International audience; Computational methods are required for prediction of non-coding RNAs (ncRNAs), which are involved in many biological processes, especially at post-transcriptional level. Among these ncRNAs, miRNAs have been largely studied and biologists need efficient and fast tools for their identification. In particular, ab initio methods are usually required when predicting novel miRNAs. Here we present a web server dedicated for miRNA precursors identification at a large scale in genomes. It is based on an algorithm called miRNAFold that allows predicting miRNA hairpin structures quickly with high sensitivity. miRNAFold is implemented as a web server with an intuitive and user-friendly interface, as well as a standalone version. The web server is freely available at: http://EvryRNA.ibisc.univ-evry.fr/miRNAFold.
Databáze: OpenAIRE
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