Herpes encephalitis and hepatitis in pregnancy: A case report and literature review
| Autor: | Michael Geary, Maria Kennelly, Claire M. McCarthy, Richard J. Drew, Caroline Conlon, Stephen Stewart |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Hepatitis
Pregnancy Pediatrics medicine.medical_specialty 030219 obstetrics & reproductive medicine Proteinuria business.industry Persistent fever Obstetrics and Gynecology 030204 cardiovascular system & hematology medicine.disease 03 medical and health sciences 0302 clinical medicine Cases medicine Gestation Initial treatment Elevated transaminases medicine.symptom business Encephalitis |
| Zdroj: | Obstet Med |
| ISSN: | 1753-4968 1753-495X |
| Popis: | We present the case of a healthy nulliparous woman who presented with persistent fever, proteinuria and elevated transaminases at 33 weeks’ gestation. Following initial treatment for suspected chorioamnionitis and potential pre-eclampsia, she had a caesarean section delivering a healthy male infant. However, on her third post-operative day, she developed neurological symptoms and accompanying severe sepsis, necessitating inotropic support and transfer to a higher level of care. A comprehensive work-up revealed herpes simplex Virus-2 (HSV-2) in serum and cerebrospinal fluid. Abdominal imaging was suggestive of accompanying hepatitis with micro-abscesses. This lady recovered well following intravenous acyclovir for 14 days. Her infant was not affected and was discharged home with his mother. Herpes simplex encephalitis and hepatitis associated with HSV-2 have been described three times previously in pregnancy. We delineate the diagnostic challenges that rare conditions such as this pose and emphasise the importance of multi-disciplinary care in managing complicated medical conditions in pregnancy. |
| Databáze: | OpenAIRE |
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