Noncontrast-enhanced renal angiography using multiple inversion recovery and alternating TR balanced steady-state free precession

Autor: Dwight G. Nishimura, Shreyas S. Vasanawala, R. Reeve Ingle, Hattie Zhi Chen Dong, Pauline W. Worters, Holden H. Wu
Rok vydání: 2012
Předmět:
Zdroj: Magnetic Resonance in Medicine. 70:527-536
ISSN: 0740-3194
DOI: 10.1002/mrm.24480
Popis: Noncontrast-enhanced renal angiography techniques based on balanced steady-state free precession avoid external contrast agents, take advantage of high inherent blood signal from the T 2 / T 1 contrast mechanism, and have short steady-state free precession acquisition times. However, background suppression is limited; inflow times are inflexible; labeling region is difficult to define when tagging arterial flow; and scan times are long. To overcome these limitations, we propose the use of multiple inversion recovery preparatory pulses combined with alternating pulse repetition time balanced steady-state free precession to produce renal angiograms. Multiple inversion recovery uses selective spatial saturation followed by four nonselective inversion recovery pulses to concurrently null a wide range of background T 1 species while allowing for adjustable inflow times; alternating pulse repetition time steady-state free precession maintains vessel contrast and provides added fat suppression. The high level of suppression enables imaging in three-dimensional as well as projective two-dimensional formats, the latter of which has a scan time as short as one heartbeat. In vivo studies at 1.5 T demonstrate the superior vessel contrast of this technique.
Databáze: OpenAIRE