Towards a Human Cell Atlas: Taking Notes from the Past
| Autor: | Aviv Regev, Sarah A. Teichmann, Rik G.H. Lindeboom |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
0303 health sciences
Cellular composition Genome Human Cells Human physiology Human cell Biology Data science Cell Physiological Phenomena 03 medical and health sciences Human health 0302 clinical medicine Human Genome Project Genetics Milestone (project management) Humans Reference map Cell Lineage 030217 neurology & neurosurgery 030304 developmental biology |
| Zdroj: | Trends in Genetics. 37:625-630 |
| ISSN: | 0168-9525 |
| Popis: | Comprehensively characterizing the cellular composition and organization of tissues has been a long-term scientific challenge that has limited our ability to study fundamental and clinical aspects of human physiology. The Human Cell Atlas (HCA) is a global collaborative effort to create a reference map of all human cells as a basis for both understanding human health and diagnosing, monitoring, and treating disease. Many aspects of the HCA are analogous to the Human Genome Project (HGP), whose completion presents a major milestone in modern biology. To commemorate the HGP's 20-year anniversary of completion, we discuss the launch of the HCA in light of the HGP, and highlight recent progress by the HCA consortium. |
| Databáze: | OpenAIRE |
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