Blocking effect of verapamil on conduction over a catecholamine-sensitive bypass tract in exercise-induced Wolff-Parkinson-White syndrome
| Autor: | Koshi Matsuyama, Yasuhiro Morikami, Atsumi Hirata, Kyoji Takaoka, Manabu Rokutanda, Shukuro Araki, Kiyotaka Kugiyama, Hideo Uchida, Ken Okumura, Yutaka Horio |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Adult
Male Cardiac pacing Intravenous bolus Electrocardiography Catecholamines Heart Conduction System Oral administration Humans Medicine medicine.diagnostic_test business.industry Cardiac Pacing Artificial Isoproterenol Inward calcium Middle Aged Verapamil Anesthesia Exercise Test Catecholamine Female Wolff-Parkinson-White Syndrome Cardiology and Cardiovascular Medicine business medicine.drug |
| Zdroj: | Journal of the American College of Cardiology. 4:186-191 |
| ISSN: | 0735-1097 |
| DOI: | 10.1016/s0735-1097(84)80340-x |
| Popis: | By intravenous administration of isoproterenol, 0.5 micrograms/min, a catecholamine-sensitive bypass tract was confirmed in two patients with exercise-induced Wolff-Parkinson-White syndrome. In a 24 year old woman, an intravenous bolus injection of 5 mg of verapamil suddenly blocked conduction over a catecholamine-sensitive bypass tract. In a 62 year old man, the exercise-induced Wolff-Parkinson-White syndrome disappeared after 3 days of oral administration of verapamil (120 mg/day). These observations suggest that a slow inward calcium current plays an important role in conduction over a catecholamine-sensitive bypass tract in exercise-induced Wolff-Parkinson-White syndrome. |
| Databáze: | OpenAIRE |
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