Comparison of nanoemulsion and non-emollient artificial tears on tear lipid layer thickness and symptoms
| Autor: | Nick Fogt, Jennifer Swingle Fogt, Kimberly Weisenberger |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Adult
Lágrimas artificiales medicine.medical_specialty genetic structures medicine.medical_treatment Síndrome del ojo seco Eye Lubricant Eye Drops 03 medical and health sciences 0302 clinical medicine Ophthalmology Eye drops Lipid layer thickness medicine Humans Grosor de la capa lipídica Dry eye disease business.industry Drop (liquid) Mean age Eye drop Middle Aged Artificial tears Lipids Gotas oftálmicas eye diseases Tears 030221 ophthalmology & optometry Dry Eye Syndromes Female Original Article sense organs Ophthalmic Solutions business 030217 neurology & neurosurgery Optometry |
| Zdroj: | Journal of Optometry |
| ISSN: | 1888-4296 |
| DOI: | 10.1016/j.optom.2020.03.002 |
| Popis: | Purpose Dry eye disease (DED) is often managed with over-the-counter eye drops. This study evaluated the diurnal effects of a single drop of two ocular lubricants (nanoemulsion vs. non-emollient) on tear film lipid layer thickness (LLT) and symptoms of ocular dryness. Subjects were also assessed after 1 month of nanoemulsion eye drop use. Methods Part 1 was a cross-over comparison of a nanoemulsion and a non-emollient eye drop. LLT and dry eye symptoms were measured at baseline and at 15 min, 1 h, 2 h, 4 h and 6 h after instillation of each drop. Part 2 was a 1-month observational study assessing LLT and symptoms after 30-day use of the nanoemulsion drop four times daily (qid). Results Total of 20 subjects completed the study (mean age = 45.6 ± 7.9, 15 female). Part 1 found a significant increase in average LLT 15 min after nanoemulsion drop instillation in the overall and inferior third of the tear film for subjects with baseline LLT values |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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