Review of sialic acid’s biochemistry, sources, extraction and functions with special reference to edible bird’s nest
| Autor: | Abdul Salam Babji, Alvin Jin Wei Ling, Lee Sin Chang, Jalifah Latip, Seng Joe Lim, Mamoru Koketsu |
|---|---|
| Rok vydání: | 2022 |
| Předmět: |
chemistry.chemical_classification
biology Glycoconjugate Skin whitening General Medicine N-Acetylneuraminic Acid Analytical Chemistry Sialic acid Birds chemistry.chemical_compound Ingredient Enzyme chemistry Biochemistry Sialic Acids biology.protein Animals Saliva N-Acetylneuraminic acid Neuraminidase Nest (protein structural motif) Food Science |
| Zdroj: | Food Chemistry. 367:130755 |
| ISSN: | 0308-8146 |
| DOI: | 10.1016/j.foodchem.2021.130755 |
| Popis: | Sialic acids are a group of nine-carbon α-keto acids. Sialic acid exists in more than 50 forms, with the natural types discovered as N-acetylneuraminic acid (Neu5Ac), deaminoneuraminic acid (2-keto-3-deoxy-nonulononic acid or Kdn), and N-glycolylneuraminic acid (Neu5Gc). Sialic acid level varies depending on the source, where edible bird's nest (EBN), predominantly Neu5Ac, is among the major sources of sialic acid. Due to its high nutritive value and complexity, sialic acid has been studied extensively through acid, aqueous, and enzymatic extraction. Although detection by chromatographic methods or mass spectrometry is common, the isolation and recovery work remained limited. Sialic acid is well-recognised for its bioactivities, including brain and cognition development, immune-enhancing, anti-hypertensive, anticancer, and skin whitening properties. Therefore, sialic acid can be used as a functional ingredient in the various industries. This paper reviews the current trend in the biochemistry, sources, extraction, and functions of sialic acids with special reference to EBN. |
| Databáze: | OpenAIRE |
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