Treatment Outcome of Resection of Disseminated Peritoneal Metastases from Colorectal Cancer
| Autor: | Shunsuke Imanishi, Hideaki Miyauchi, Toshiharu Hanaoka, Gaku Ohira, Michihiro Maruyama, Koichiro Okada, Hisahiro Matsubara, Tetsuro Maruyama, Toru Tochigi, Koichi Hayano |
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| Rok vydání: | 2020 |
| Předmět: |
Cancer Research
medicine.medical_specialty Peritoneal metastasis Adjuvant chemotherapy Colorectal cancer Treatment outcome Gastroenterology General Biochemistry Genetics and Molecular Biology Resection Internal medicine medicine Humans Colorectal adenocarcinoma Peritoneal Neoplasms Retrospective Studies Pharmacology business.industry Nodule (medicine) Prognosis medicine.disease Survival Rate Treatment Outcome Neoplasm Recurrence Local medicine.symptom Colorectal Neoplasms business Carbohydrate antigen Research Article |
| Zdroj: | In Vivo |
| ISSN: | 1791-7549 0258-851X |
| Popis: | Aim To show the treatment outcomes of disseminated nodule resection for peritoneal metastasis of colorectal cancer and describe the details of cured cases. Patients and methods From January 2001 to December 2016, patients who underwent disseminated nodule resection of colorectal adenocarcinoma with no macroscopic residual tumor in our institution were retrospectively analyzed for clinicopathological factors associated with prognosis. Results Forty-one cases were included in this study. The 3-year relapse-free survival was 12.5%, and the 5-year overall survival was 38.4%. In a multivariate analysis, lack of post-operative adjuvant chemotherapy and pre-operative carbohydrate antigen 19-9 over 100 IU/l were extracted as independent factors associated with short relapse-free survival, respectively. Among 41 cases, 32 were followed-up 5 years after surgery and five (15.6%) survived without relapse and were regarded as 'cured'. Conclusion More than a few cases of colorectal peritoneal metastasis, which is thought to be difficult to cure, were cured by resection of disseminated nodules without resorting to highly invasive treatment. |
| Databáze: | OpenAIRE |
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