Effects of immunotherapy with a purified standardized allergen preparation of Dermatophagoides farinae in adults with perennial allergic rhinoconjunctivitis
| Autor: | B. Agrell, Thorvald Löfkvist, G. Svensson, S. Dreborg |
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| Rok vydání: | 1994 |
| Předmět: |
Adult
Allergy Rhinitis Allergic Perennial medicine.medical_treatment Immunology Immunoglobulin E medicine.disease_cause chemistry.chemical_compound Allergen Mite Immunology and Allergy Medicine Animals Humans Antigens Dermatophagoides Desensitization (medicine) Conjunctivitis Allergic Glycoproteins Skin Tests Mites biology business.industry Pyroglyphidae Antibody titer Allergens biology.organism_classification medicine.disease chemistry Desensitization Immunologic Immunoglobulin G biology.protein business Histamine |
| Zdroj: | Allergy. 49(2) |
| ISSN: | 0105-4538 |
| Popis: | Immunotherapy (IT) was performed for 12 months with a purified and standardized preparation of Dermatophagoides farinae. Twenty adults with rhinoconjunctivitis sensitive to house-dust mite were given IT, and a similar group of 11 patients served as open controls. A total of 512 injections were given. Twenty-eight episodes of allergic side-effects occurred, 13 general and 15 local, most of them during the initial incremental dose period. No severe reactions started later than 30 min after the injection. One patient suffered anaphylactic shock. In this patient, specific antibodies fell immediately, followed by an increase within 1 week. The therapy group improved significantly in relation to the open controls in patients’ subjective evaluation of symptoms (P |
| Databáze: | OpenAIRE |
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