Prognostic Value Of Blood Cultures as an Illness Severity Marker In Emergency Medical Admissions
| Autor: | Deirdre O'Riordan, Bernard Silke, Declan Byrne, Brian O'Connell, Richard Conway |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Hospital mortality Critical Care and Intensive Care Medicine Logistic regression 030226 pharmacology & pharmacy Severity of Illness Index 03 medical and health sciences 0302 clinical medicine Internal medicine Severity of illness Internal Medicine medicine Illness severity Humans Blood culture Hospital Mortality medicine.diagnostic_test business.industry General Medicine medicine.disease Prognosis Comorbidity Blood Culture 030220 oncology & carcinogenesis Emergency Medicine Positive culture Culture negative business Emergency Service Hospital |
| Zdroj: | Europe PubMed Central Scopus-Elsevier |
| ISSN: | 1747-4892 |
| Popis: | Background: Positive blood cultures predict mortality. The prognostic value of blood culture performance itself has not been fully defined. Methods: We evaluated medical admissions from 2002-2017. We defined blood culture category as 1) no culture 2) negative culture 3) positive culture. We employed a multivariable logistic regression model to evaluate outcomes. Results: We evaluated 78,568 blood cultures in 106,586 admissions. 30-day in-hospital mortality for no culture was 2.8% (95%CI 2.7, 2.9), culture negative 8.9% (95%CI 8.5, 9.3) and culture positive 16.7% (95%CI 15.5, 17.9). There was significant interaction between blood culture category and illness severity, OR 1.06 (95%CI 1.05, 1.08), and comorbidity, OR 1.09 (95%CI 1.09, 1.10). Conclusion: Performance and results of blood cultures are independently associated with increased mortality. |
| Databáze: | OpenAIRE |
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