Activity of cholinesterases and adenosine deaminase in blood and serum of rats experimentally infected withTrypanosoma cruzi
Autor: | Maria Rosa Chitolina Schetinger, Victor Camera Pimentel, Jeandre Augusto dos Santos Jaques, C. B. da Silva, Alexandre A. Tonin, A. S. da Silva, Raqueli T. França, Vera Maria Morsch, Amanda Maino Fiorenza, Claudio A.M. Leal, Sonia Terezinha dos Anjos Lopes, Silvia Gonzalez Monteiro |
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Rok vydání: | 2011 |
Předmět: |
Male
Chagas disease medicine.medical_specialty Adenosine Deaminase Trypanosoma cruzi Antibodies Protozoan Antigens Protozoan Motor Activity Group A chemistry.chemical_compound Blood serum Adenosine deaminase Internal medicine medicine Animals Cholinesterases Chagas Disease Butyrylcholinesterase Cholinesterase biology Heart biology.organism_classification medicine.disease Acetylcholinesterase Rats Infectious Diseases Endocrinology chemistry Immunology biology.protein Original Article Parasitology |
Zdroj: | Annals of Tropical Medicine & Parasitology. 105:385-391 |
ISSN: | 1364-8594 0003-4983 |
DOI: | 10.1179/1364859411y.0000000026 |
Popis: | This study aimed to evaluate the activity of cholinesterases and adenosine deaminase (ADA) in blood and serum of rats infected with Trypanosoma cruzi. Twelve adult rats were used in the experiment divided into two uniform groups. Rodents from group A (control group) were non-infected and animals from group B served as infected, receiving intraperitoneally 3·3×10(7) trypomastigotes/each. Blood collection was performed at days 60 and 120 post-infection (PI) in order to evaluate the hemogram, blood activity of acetylcholinesterase, and serum butyrylcholinesterase and ADA activities. Hematological parameters did not differ between groups. A significant increase (P |
Databáze: | OpenAIRE |
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