Activity of cholinesterases and adenosine deaminase in blood and serum of rats experimentally infected withTrypanosoma cruzi

Autor: Maria Rosa Chitolina Schetinger, Victor Camera Pimentel, Jeandre Augusto dos Santos Jaques, C. B. da Silva, Alexandre A. Tonin, A. S. da Silva, Raqueli T. França, Vera Maria Morsch, Amanda Maino Fiorenza, Claudio A.M. Leal, Sonia Terezinha dos Anjos Lopes, Silvia Gonzalez Monteiro
Rok vydání: 2011
Předmět:
Zdroj: Annals of Tropical Medicine & Parasitology. 105:385-391
ISSN: 1364-8594
0003-4983
DOI: 10.1179/1364859411y.0000000026
Popis: This study aimed to evaluate the activity of cholinesterases and adenosine deaminase (ADA) in blood and serum of rats infected with Trypanosoma cruzi. Twelve adult rats were used in the experiment divided into two uniform groups. Rodents from group A (control group) were non-infected and animals from group B served as infected, receiving intraperitoneally 3·3×10(7) trypomastigotes/each. Blood collection was performed at days 60 and 120 post-infection (PI) in order to evaluate the hemogram, blood activity of acetylcholinesterase, and serum butyrylcholinesterase and ADA activities. Hematological parameters did not differ between groups. A significant increase (P
Databáze: OpenAIRE