Combined effects of backward treadmill training and botulinum toxin type A therapy on gait and balance in patients with chronic stroke: A pilot, single-blind, randomized controlled trial

Autor:	Marialuisa Gandolfi, Mirko Filippetti, Angela Modenese, Daniele Munari, Jacopo Disarò, Nicola Smania, Anna Serina, Alessandro Picelli
Rok vydání:	2020
Předmět:	Adult Male 030506 rehabilitation medicine.medical_specialty medicine.medical_treatment Modified Ashworth scale Physical Therapy Sports Therapy and Rehabilitation law.invention 03 medical and health sciences 0302 clinical medicine Physical medicine and rehabilitation Randomized controlled trial law medicine Humans Single-Blind Method Spasticity Botulinum Toxins Type A cerebral stroke Gait postural balance muscle spasticity Aged Balance (ability) Rehabilitation business.industry Stroke Rehabilitation Middle Aged stability Combined Modality Therapy Botulinum toxin Exercise Therapy Stroke locomotion Neuromuscular Agents Gait analysis Female Neurology (clinical) medicine.symptom 0305 other medical science business human activities 030217 neurology & neurosurgery medicine.drug
Zdroj:	NeuroRehabilitation. 46:519-528
ISSN:	1878-6448 1053-8135
DOI:	10.3233/nre-203067
Popis:	Background Backward walking is recommended to improve the components of physiological gait in neurological disease. Botulinum toxin type A is an effective safe first line-treatment for post-stroke spasticity. Objective To compare the effects of backward treadmill training (BTT) versus standard forward treadmill training (FTT) on motor impairment in patients with chronic stroke receiving botulinum toxin type A therapy. Methods Eighteen chronic stroke patients were randomly assigned to receive BTT (n = 7) or FTT (n = 11) as adjunct to botulinum toxin type A therapy. A total of twelve 40-minute sessions (3 sessions/week for 4 weeks) of either BTT or FTT were conducted. A blinded assessor evaluated the patients before and after treatment. The primary outcome was the 10-meter Walking Test (10 MWT). Secondary outcomes were the modified Ashworth Scale, gait analysis, and stabilometric assessment. Results Between-group comparison showed a significant change on the 10 MWT (P = 0.008) and on stabilometric assessment [length of centre of pressure CoP (P = 0.001) and sway area (P = 0.002) eyes open and length of CoP (P = 0.021) and sway area (P = 0.008) eyes closed] after treatment. Conclusions Greater improvement in gait and balance was noted after BTT than after FTT as an adjunct to botulinum toxin therapy in patients with chronic stroke.
Databáze:	OpenAIRE
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