Uncommon Manifestation of Hypoglycemia in a Patient with Insulinoma – A Case Report
| Autor: | Loreta Guja, Rucsandra Dănciulescu Miulescu, Georgeta Văcaru, Nicoleta Mindrescu |
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| Rok vydání: | 2019 |
| Předmět: |
endocrine system
medicine.medical_specialty endocrine system diseases medicine.medical_treatment Specialties of internal medicine insulinoma Hypoglycemia Gastroenterology Asymptomatic 03 medical and health sciences 0302 clinical medicine Diabetes mellitus Internal medicine Medicine Family history Insulinoma business.industry Insulin medicine.disease hypoglycemia RC581-951 Basal (medicine) 030220 oncology & carcinogenesis anxiety phenomena medicine.symptom business hormones hormone substitutes and hormone antagonists 030217 neurology & neurosurgery Rare disease |
| Zdroj: | Romanian Journal of Diabetes Nutrition and Metabolic Diseases, Vol 26, Iss 3, Pp 327-330 (2019) |
| ISSN: | 2284-6417 |
| DOI: | 10.2478/rjdnmd-2019-0035 |
| Popis: | Insulinoma are insulin-secreting tumors of pancreatic origin that generates hypoglycemia by excessive secretion of insulin. Insulinoma is a rare disease ant the most tumors are benign, solitary and occur at intrapancreatic sites. Case report. A 42-year old Caucasian women was hospitalized at the “Prof. N.C. Paulescu” National Institute of Diabetes, Nutrition and Metabolic Diseases Bucharest in April 2019 after an episode of hypoglycaemia remitted after intravenous glucose administration. Patient accused for about two weeks anxiety phenomena. At the time of admission in the hospital the patient was conscious in a good general condition. Paraclinical investigations revealed basal blood glucose 29 mg/dl, fasting insulin serum 87.7 µU/ml and pancreatic C-peptide-7.90 ng/ml. During hospitalization under strict glycaemic monitoring, the patient presented frequent asymptomatic hypoglycemic episodes that was remitted after intravenous glucose administration. Nuclear magnetic resonance highlighted a nodular lesion of the pancreas and in May 2019 the tumor resection was practiced. After surgery the blood glucose ranged between 86 mg/dl and 116 mg/dl. To mention that patient has a family history of diabetes and she’s obese. Conclusion. This case suggests that lack symptoms of hypoglycaemia may be present in patients with insulinoma. Diagnostic of insulinoma requires high clinical suspicions, accurate biochemical investigations and imaging techniques for the localization of the tumor and may represent a challenge in certain situations. |
| Databáze: | OpenAIRE |
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