Evaluation of a guideline directed medical therapy titration program in patients with heart failure with reduced ejection fraction
| Autor: | Richard Soucier, Aadhar Patil, Shannon P. Marsh, Kathir Balakumaran, Sabeena Arora, Chia-Ling Kuo, Daniel Jacoby, Joseph Ingrassia |
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| Rok vydání: | 2019 |
| Předmět: |
lcsh:Diseases of the circulatory (Cardiovascular) system
medicine.medical_specialty Renal function 030204 cardiovascular system & hematology Implantable defibrillator Single Center 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Internal medicine Medicine 030212 general & internal medicine Original Paper Ejection fraction Aldosterone biology business.industry Angiotensin-converting enzyme Guideline medicine.disease chemistry lcsh:RC666-701 Heart failure biology.protein Cardiology and Cardiovascular Medicine business |
| Zdroj: | International Journal of Cardiology: Heart & Vasculature, Vol 22, Iss, Pp 1-5 (2019) International Journal of Cardiology. Heart & Vasculature |
| ISSN: | 2352-9067 |
| DOI: | 10.1016/j.ijcha.2018.10.003 |
| Popis: | Introduction: Heart failure is associated with recurrent hospitalizations and high mortality. Guideline directed medical treatment (GDMT), including beta blockers (BBs), angiotensin converting enzyme inhibitors (ACE-Is), angiotensin receptor blockers (ARBs) and aldosterone antagonists (AAs) has shown to improve outcomes. Current guidelines recommend the use of these medication classes at maximally tolerated dosages. Despite the evidence, 90 days) compiled 48% of the patient population. Patients with NYHA class III heart failure compiled 65% of the patient population.There was a statistically significant increase in the mean number of GDMT at any dose (2.31 ± 0.76 to 2.74 ± 0.66; p |
| Databáze: | OpenAIRE |
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