European registry of type A aortic dissection (ERTAAD) - rationale, design and definition criteria

Autor: Tatu Juvonen, Sidney Chocron, Stefano Mastrobuoni, Christian Detter, Suvitesh Luthra, Mauro Rinaldi, Francesco Onorati, Zein El Dean, Angelo M. Dell’Aquila, Giovanni Mariscalco, Matteo Pettinari, Alessandra Francica, Antonio Fiore, Luisa Ferrante, Antti Vento, Andrea Perrotti, Marek Pol, Laurent de Kerchove, Hakeem Yusuff, Steven Laga, Thierry Folliguet, Cecilia Rossetti, Amer Harky, Fausto Biancari, Thilo Noack, Ugolino Livi, Filip Schlosser, Stefano Forlani, Geoffrey Tsang, Lenard Conradi, Govind Chetty, Mikko Jormalainen, Manoj Kuduvalli, Till Demal, Peter Ivak, Peter Raivio, Mark Field, Igor Vendramin, Christian D. Etz, Marc A.A.M. Schepens, Bart Meuris, Michael A. Borger
Přispěvatelé: UCL - SSS/IREC/CARD - Pôle de recherche cardiovasculaire, UCL - (SLuc) Service de chirurgie cardiovasculaire et thoracique, HUS Heart and Lung Center, University of Helsinki, Department of Surgery, III kirurgian klinikka, Clinicum
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Male
Cardiac & Cardiovascular Systems
Aortic dissection
Comorbidity
030204 cardiovascular system & hematology
law.invention
Study Protocol
0302 clinical medicine
Postoperative Complications
Clinical Protocols
Aortic arch
law
Risk Factors
Anesthesiology
EQUATION
RD78.3-87.3
Hospital Mortality
Registries
Stroke
Aged
80 and over
HEMIARCH
Acute kidney injury
General Medicine
Middle Aged
Prognosis
Intensive care unit
3. Good health
Cardiac surgery
Aortic Aneurysm
Europe
REPLACEMENT
Cardiothoracic surgery
Research Design
Female
Cardiology and Cardiovascular Medicine
Life Sciences & Biomedicine
Pulmonary and Respiratory Medicine
Adult
Reoperation
medicine.medical_specialty
Stanford type A
RD1-811
03 medical and health sciences
Aneurysm
Dissecting
medicine
Humans
Adverse effect
Aged
Retrospective Studies
Ascending aorta
Emergency
Science & Technology
INTERNATIONAL REGISTRY
business.industry
Correction
Perioperative
medicine.disease
3126 Surgery
anesthesiology
intensive care
radiology
030228 respiratory system
Emergency medicine
Cardiovascular System & Cardiology
Vascular Grafting
Surgery
Human medicine
business
Zdroj: Journal of Cardiothoracic Surgery, Vol 16, Iss 1, Pp 1-9 (2021)
Journal of Cardiothoracic Surgery
Journal of cardiothoracic surgery, Vol. 16, no.1, p. 171 [1-9] (2021)
Journal of cardiothoracic surgery
ISSN: 1749-8090
Popis: Background Acute Stanford type A aortic dissection (TAAD) is a life-threatening condition. Surgery is usually performed as a salvage procedure and is associated with significant postoperative early mortality and morbidity. Understanding the patient’s conditions and treatment strategies which are associated with these adverse events is essential for an appropriate management of acute TAAD. Methods Nineteen centers of cardiac surgery from seven European countries have collaborated to create a multicentre observational registry (ERTAAD), which will enroll consecutive patients who underwent surgery for acute TAAD from January 2005 to March 2021. Analysis of the impact of patient’s comorbidities, conditions at referral, surgical strategies and perioperative treatment on the early and late adverse events will be performed. The investigators have developed a classification of the urgency of the procedure based on the severity of preoperative hemodynamic conditions and malperfusion secondary to acute TAAD. The primary clinical outcomes will be in-hospital mortality, late mortality and reoperations on the aorta. Secondary outcomes will be stroke, acute kidney injury, surgical site infection, reoperation for bleeding, blood transfusion and length of stay in the intensive care unit. Discussion The analysis of this multicentre registry will allow conclusive results on the prognostic importance of critical preoperative conditions and the value of different treatment strategies to reduce the risk of early adverse events after surgery for acute TAAD. This registry is expected to provide insights into the long-term durability of different strategies of surgical repair for TAAD. Trial registration ClinicalTrials.gov Identifier: NCT04831073.
Databáze: OpenAIRE
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