Enhancing K+ transport activity and selectivity of synthetic K+ channels via electron-donating effects

Autor:	Tianxiang Wang, Landley Ziluo Zeng, Tianhu Li, Hao Zhang
Přispěvatelé:	School of Physical and Mathematical Sciences
Rok vydání:	2020
Předmět:	Transport activity Chemistry Room-Temperature Gelation Metals and Alloys General Chemistry Electron Ion Channels Catalysis Surfaces Coatings and Films Electronic Optical and Magnetic Materials Crystallography Chemistry [Science] Materials Chemistry Ceramics and Composites Selectivity K channels
Zdroj:	Chemical Communications. 56:1211-1214
ISSN:	1364-548X 1359-7345
Popis:	A minor alteration in structure of a previously reported synthetic K+ channel via replacing the electron-withdrawing group with an electron-donating group leads to enhancement in activity by 160% and in selectivity by >50%. As a result, the new K+ channel 10F5, despite having a simple structure, exhibits a high K+/Na+ selectivity of 14.0. Agency for Science, Technology and Research (A*STAR) This work is funded by the Agency for Science, Technology and Research, Singapore (SERC A1883c0007 to T. L.).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f462ae3b08f08e783b9a1cd27887aff5 https://doi.org/10.1039/c9cc08396k Zobrazit plný text záznamu