High–Dose Pulse Versus Nonpulse Corticosteroid Regimens in Severe Acute Respiratory Syndrome
| Autor: | Kenneth W. Tsang, Johnny W.M. Chan, Ivan Hung, Moira Chan-Yeung, Poon Chuen Wong, Wah K. Lam, Thomas Y.W. Mok, James Chung-Man Ho, Mary S. Ip, Pak L. Ho, Bing Lam, Gaik C. Ooi, Chun K. Ng, Patrick C.K. Li, Kar N. Lai |
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| Rok vydání: | 2003 |
| Předmět: |
Adult
Male Pulmonary and Respiratory Medicine medicine.medical_specialty medicine.drug_class Secondary infection medicine.medical_treatment Anti-Inflammatory Agents Severe Acute Respiratory Syndrome Critical Care and Intensive Care Medicine Antiviral Agents Methylprednisolone law.invention Cohort Studies law Intensive care Ribavirin medicine Humans Aged Retrospective Studies Mechanical ventilation business.industry Middle Aged medicine.disease Intensive care unit Surgery Regimen Treatment Outcome Pulse Therapy Drug Atypical pneumonia Anesthesia Corticosteroid Female business medicine.drug |
| Zdroj: | American Journal of Respiratory and Critical Care Medicine. 168:1449-1456 |
| ISSN: | 1535-4970 1073-449X |
| DOI: | 10.1164/rccm.200306-766oc |
| Popis: | The treatment of atypical pneumonia, subsequently termed severe acute respiratory syndrome (SARS), is controversial, and the efficacy of corticosteroid therapy is unknown. We have evaluated the clinical and radiographic outcomes of 72 patients with probable SARS (median age 37 years, 30 M), who received ribavirin and different steroid regimens in two regional hospitals. Chest radiographs were scored according to the percentage of lung field involved. Seventeen patients initially received pulse steroid (PS) (methylprednisolone > or =500 mg/day) and 55 patients initially received nonpulse steroid (NPS) (methylprednisolone |
| Databáze: | OpenAIRE |
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