Weighing In: Emergent Diabetes Mellitus and Second-Generation Antipsychotics

Autor: Robert L. Dufresne
Rok vydání: 2007
Předmět:
Zdroj: Annals of Pharmacotherapy. 41:1725-1727
ISSN: 1542-6270
1060-0280
DOI: 10.1345/aph.1k362
Popis: Of all the metabolic effects of some of the atypical second-generation antipsychotics, their potential to induce glucose dysregulation has induced a storm of controversy over the past several years. The numerous published epidemiologic studies are difficult to interpret due to the high background rate of type 2 diabetes mellitus in this population, the inherent problems with analysis of observational data, and the short duration of the available studies. A plan to monitor for weight gain, hypertriglyceridemia, glucose dysregulation, and other potential adverse metabolic effects resulting from antipsychotic treatment is critical.
Databáze: OpenAIRE