Weighing In: Emergent Diabetes Mellitus and Second-Generation Antipsychotics
Autor: | Robert L. Dufresne |
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Rok vydání: | 2007 |
Předmět: |
medicine.medical_specialty
medicine.medical_treatment Population 030204 cardiovascular system & hematology Antipsychotic treatment Weight Gain 030226 pharmacology & pharmacy 03 medical and health sciences 0302 clinical medicine Diabetes mellitus Internal medicine Diabetes Mellitus medicine Animals Humans Pharmacology (medical) Obesity Antipsychotic Intensive care medicine education education.field_of_study business.industry Hypertriglyceridemia Type 2 Diabetes Mellitus medicine.disease Endocrinology Observational study business Antipsychotic Agents |
Zdroj: | Annals of Pharmacotherapy. 41:1725-1727 |
ISSN: | 1542-6270 1060-0280 |
DOI: | 10.1345/aph.1k362 |
Popis: | Of all the metabolic effects of some of the atypical second-generation antipsychotics, their potential to induce glucose dysregulation has induced a storm of controversy over the past several years. The numerous published epidemiologic studies are difficult to interpret due to the high background rate of type 2 diabetes mellitus in this population, the inherent problems with analysis of observational data, and the short duration of the available studies. A plan to monitor for weight gain, hypertriglyceridemia, glucose dysregulation, and other potential adverse metabolic effects resulting from antipsychotic treatment is critical. |
Databáze: | OpenAIRE |
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