Prediction of malignant transformation in oral epithelial dysplasia using machine learning

Autor: James Ingham, Caroline I Smith, Barnaby G Ellis, Conor A Whitley, Asterios Triantafyllou, Philip J Gunning, Steve D Barrett, Peter Gardener, Richard J Shaw, Janet M Risk, Peter Weightman
Rok vydání: 2022
Předmět:
Zdroj: IOP SciNotes. 3(3)
ISSN: 2633-1357
Popis: A machine learning algorithm (MLA) has been applied to a Fourier transform infrared spectroscopy (FTIR) dataset previously analysed with a principal component analysis (PCA) linear discriminant analysis (LDA) model. This comparison has confirmed the robustness of FTIR as a prognostic tool for oral epithelial dysplasia (OED). The MLA is able to predict malignancy with a sensitivity of 84 ± 3% and a specificity of 79 ± 3%. It provides key wavenumbers that will be important for the development of devices that can be used for improved prognosis of OED.
Databáze: OpenAIRE