Platelet Function and Fibrinolytic Activity Following Distance Running
| Autor: | J. Bjerre Knudsen, Robert Jordal, K. Nørregaard-Hansen, P.-E. Paulev, U. Brodthagen, Johs. Gormsen |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Adult
Male Serotonin medicine.medical_specialty Time Factors Platelet Aggregation Platelet Function Tests Platelet aggregation Strenuous exercise Platelet Factor 4 Running Distance running Internal medicine Euglobulin lysis time Humans Medicine Platelet Long distance runners business.industry Fibrinolysis Antithrombin Hematology Middle Aged Surgery Adenosine Diphosphate Endocrinology business human activities Platelet factor 4 medicine.drug |
| Zdroj: | Scandinavian Journal of Haematology. 29:425-430 |
| ISSN: | 0036-553X |
| Popis: | 6 long distance runners from the Danish marathon elite and 6 non-runners completed test runs of 28 and 12 km, respectively. Distance runners and non-runners showed the same responses in platelet function. We found a significant decrease in ADP induced platelet aggregability, a decreased serotonin release induced by ADP and collagen and an increase in platelet factor 4 immediately following the run. The antithrombin III levels remained constant. Euglobulin lysis time was shortened (by approximately 50 %) and the plasminogen levels significantly increased. The last 2 findings indicate an equal increase in fibrinolytic activity during distance running in both groups. While short term, strenuous exercise induces platelet hyperaggregation, long term distance running induces a state of exhaustion of platelet aggregation capacity. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|