Tumour size over 3 cm predicts poor short-term outcomes after major liver resection for hilar cholangiocarcinoma. By the HC-AFC-2009 group

Autor: Laurence Chiche, Mustapha Adham, Jeanâ€Robert Delpero, Patrick Pessaux, Emmanuel Boleslawski, Daniel Azoulay, Denis Chatelain, Michel Scotté, Karim Boudjema, Alexis Laurent, Jean-Marc Regimbeau, Philippe Bachellier, Gérard Pascal, Jeanâ€Yves Mabrut, Momar Diouf, Olivier Farges, Gennaro Nuzzo, Christian Letoublon, Georges Mantion, Jeanâ€Francois Gigot, Yvesâ€Patrice Le Treut, Artigas Raventos, Francis Navarro, Michel Rivoire, Ahmet Ayav, David Fuks
Přispěvatelé: CHU Amiens-Picardie, CHU Strasbourg, Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), Service de Chirurgie Viscérale et Digestive [CHU Caen], CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN)-Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN), Hôpital Paul Brousse, Université Paris-Sud - Paris 11 (UP11)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse, Hôpital Henri Mondor, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Henri Mondor-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Département de chirurgie digestive et de l'urgence, CHU Grenoble-Hôpital Michallon, Hôpital Claude Huriez [Lille], CHU Lille, Centre Léon Bérard [Lyon], Hôpital de la Croix-Rousse [CHU - HCL], Hospices Civils de Lyon (HCL), Hôpital Edouard Herriot [CHU - HCL], Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC), Hôpital de la Conception [CHU - APHM] (LA CONCEPTION), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Cellules Souches, Plasticité Cellulaire, Médecine Régénératrice et Immunothérapies (IRMB), Université de Montpellier (UM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Service de Chirurgie Digestive Hépatobiliaire et Endocrine [CHRU Nancy], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), CHU Pontchaillou [Rennes], Service de chirurgie digestive [CHU Rouen], CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU), Hôpital Beaujon, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Diderot - Paris 7 (UPD7)-Hôpital Beaujon [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Herrada, Anthony
Rok vydání: 2015
Předmět:
Male
Curative resection
Time Factors
[SDV.MHEP.CHI] Life Sciences [q-bio]/Human health and pathology/Surgery
medicine.medical_treatment
Kaplan-Meier Estimate
030230 surgery
Cholangiocarcinoma
0302 clinical medicine
Risk Factors
Odds Ratio
Registries
Young adult
Aged
80 and over
Gastroenterology
Middle Aged
Tumor Burden
3. Good health
Treatment Outcome
030220 oncology & carcinogenesis
Female
France
Adult
medicine.medical_specialty
[SDV.MHEP.CHI]Life Sciences [q-bio]/Human health and pathology/Surgery
Resection
Young Adult
03 medical and health sciences
medicine
Hepatectomy
Humans
Aged
Retrospective Studies
Chi-Square Distribution
Hepatology
business.industry
[SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology
Retrospective cohort study
Original Articles
Odds ratio
[SDV.MHEP.HEG] Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology
Surgery
Bile Ducts
Intrahepatic
Logistic Models
Bile Duct Neoplasms
Tumour size
Multivariate Analysis
Lymph Node Excision
business
Chi-squared distribution
Zdroj: HPB
HPB, Wiley, 2015, 17 (1), pp.79-86. ⟨10.1111/hpb.12296⟩
HPB, Elsevier, 2015, 17 (1), pp.79-86. ⟨10.1111/hpb.12296⟩
ISSN: 1365-182X
1477-2574
DOI: 10.1111/hpb.12296
Popis: International audience; INTRODUCTION:As mortality and morbidity after a curative resection remains high, it is essential to identify pre-operative factors associated with an early death after a major resection.METHODS:Between 1998 and 2008, we selected a population of 331 patients having undergone a major hepatectomy including segment I with a lymphadenectomy and a common bile duct resection for a proven hilar cholangiocarcinoma in 21 tertiary centres. The study's objective was to identify pre-operative predictors of early death (30 mm [odds ratio (OR) 2.471 (95% confidence interval (CI) 1.136-7.339), P = 0.001] and major post-operative complication [OR 3.369 (95% CI 1.038-10.938), P = 0.004] were independently associated with death 30 mm was independently associated with death
Databáze: OpenAIRE
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