Cryoglobulinemic glomerulonephritis in chronic hepatitis B infection

Autor:	E Andrada, C Escolano, Félix Gutiérrez, Juan Carlos Rodríguez, A E Sirvent, R Enríquez, Isabel Millán, F Amorós
Rok vydání:	2010
Předmět:	Adult Nephrotic Syndrome Biopsy Critical Care and Intensive Care Medicine medicine.disease_cause Antiviral Agents Diagnosis Differential Glomerulonephritis Hepatitis B Chronic Medicine Humans Hepatitis B virus medicine.diagnostic_test business.industry Lamivudine General Medicine Hepatitis B medicine.disease Cryoglobulinemia Nephrology Immunology Female Liver function Renal biopsy business Nephrotic syndrome medicine.drug
Zdroj:	Renal failure. 32(4)
ISSN:	1525-6049
Popis:	Hepatitis B virus (HBV) infection is an uncommon cause of cryoglobulinemia. Renal cryoglobulinemia has been rarely reported in the setting of chronic hepatitis B infection. We describe a case of chronic hepatitis B infection with cryoglobulinemic glomerulonephritis (Gn) and provide information about the treatment and the evolution over a 30-month follow-up. A 41-year-old woman with chronic hepatitis B infection developed nephrotic syndrome and acute renal failure; other investigations revealed type 2 cryoglobulinemia; HBV DNA was detected in the cryoprecipitate. Renal biopsy showed findings of cryoglobulinemic Gn. She was given lamivudine, corticosteroids, plasma exchange, and mycophenolate mofetil. The renal function improved, nephrotic syndrome remitted, and HBV DNA became undetectable; there was no compromise of the liver function.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f44e804f15b4081b62b9ff3499009da0 https://pubmed.ncbi.nlm.nih.gov/20446795 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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