Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021

Autor: Janice L. Zimmerman, Michael A. Puskarich, Luciano Cesar Pontes Azevedo, Derek C. Angus, Michael Klompas, John Centofanti, Laura Evans, Elizabeth Papathanassoglou, Gregory J. Beilman, Yaseen M. Arabi, Craig French, W. Joost Wiersinga, Maureen A. Seckel, Mark E. Nunnally, Suzana Margareth Lobo, Lisa Burry, Shevin T. Jacob, Jason A. Roberts, Richard Beale, Emilie P. Belley-Côté, Anders Perner, Waleed Alhazzani, Angel Coz Yataco, Jonathan E. Sevransky, Elisa Estenssoro, Kent Doi, Craig M. Coopersmith, Steven McGloughlin, Tiffany M. Osborn, Henry Masur, Maurizio Cecconi, Sangeeta Mehta, Morten Hylander Møller, Charles D. Gomersall, Jan De Waele, Mitchell M. Levy, Andrew Rhodes, Tobias Welte, R. Phillip Dellinger, Steven Q. Simpson, Theodore J. Iwashyna, Anand Kumar, Flávia Ribeiro Machado, Yatin Mehta, Arthur Kwizera, Ruth M. Kleinpell, Fayez Alshamsi, Hallie C. Prescott, William D. Schweickert, Charles L. Sprung, Younsuck Koh, Simon Oczkowski, Massimo Antonelli, Ricard Ferrer, Lauralyn McIntyre, Mervyn Mer, Christa Schorr, Marlies Ostermann, Bin Du, Carol L. Hodgson
Přispěvatelé: Center of Experimental and Molecular Medicine, Infectious diseases, AII - Infectious diseases
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Blood Glucose
Surviving Sepsis Campaign
Organ Dysfunction Scores
wa_530
Critical Care and Intensive Care Medicine
Severity of Illness Index
Anti-Infective Agents
Reference Values
Septic shock
Vasoactive
Electronic Health Records
Vasoconstrictor Agents
Grading (education)
Drug Administration Routes
Shock
Septic
Renal Replacement Therapy
Intensive Care Units
Practice Guidelines as Topic
Erythrocyte Transfusion
evidence-based medicine
medicine.medical_specialty
Cardiotonic Agents
Critical Care
wc_240
Resuscitation
Urology
Best practice
MEDLINE
Immunoglobulins
Guidelines
Drug Administration Schedule
Time-to-Treatment
Diagnosis
Differential
Sepsis
Anesthesiology
Settore MED/41 - ANESTESIOLOGIA
Severity of illness
medicine
Humans
Adults
Arterial Pressure
Lactic Acid
Intensive care medicine
business.industry
wa_525
Hemodynamics
Evidence-based medicine
medicine.disease
Respiration
Artificial
Evidence based medicine
Fluid Therapy
business
Biomarkers
Zdroj: Critical care medicine, 49(11), e1063-e1143. Lippincott Williams and Wilkins
Intensive Care Medicine
Intensive care medicine, 47(11), 1181-1247. Springer Verlag
ISSN: 0090-3493
0342-4642
Popis: Background\ud Sepsis poses a global threat to millions of lives. The Surviving Sepsis Campaign (SSC) guidelines provide evidence-based recommendations on the recognition and management of sepsis and its complications.\ud Methods\ud We formed a panel of 60 experts from 22 countries and 11 members of the public. The panel prioritized questions that are relevant to the recognition and management of sepsis and septic shock in adults. New questions and sections were addressed, relative to the previous guidelines. These questions were grouped under 6 subgroups (screening and early treatment, infection, hemodynamics, ventilation, additional therapies, and long-term outcomes and goals of care). With input from the panel and methodologists, professional medical librarians performed the search strategy tailored to either specific questions or a group of relevant questions. A dedicated systematic review team performed screening and data abstraction when indicated. For each question, the methodologists, with input from panel members, summarized the evidence assessed and graded the quality of evidence using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach. The panel generated recommendations using the evidence-to-decision framework. Recommendations were either strong or weak, or in the form of best practice statements. When evidence was insufficient to support a recommendation, the panel was surveyed to generate “in our practice” statements.\ud Results\ud The SSC panel issued 93 statements: 15 best practice statements, 15 strong recommendations, and 54 weak recommendations and no recommendation was provided for 9 questions. The recommendations address several important clinical areas related to screening tools, acute resuscitation strategies, management of fluids and vasoactive agents, antimicrobials and diagnostic tests and the use of additional therapies, ventilation management, goals of care, and post sepsis care.\ud Conclusion\ud The SSC panel issued evidence-based recommendations to help support key stakeholders caring for adults with sepsis or septic shock and their families.
Databáze: OpenAIRE
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