Age-dependent accuracy of Helicobacter pylori antibody assays for adults, with special emphasis on atrophic gastritis

Autor:	Seppo Sarna, J. Mattila, Hilpi Rautelin, Timo U. Kosunen, Anniina Salomaa-Räsänen
Rok vydání:	2004
Předmět:	Microbiology (medical) Adult Gastritis Atrophic Male medicine.medical_specialty Adolescent Atrophic gastritis Clinical Biochemistry Immunology Age dependent Gastroenterology Sensitivity and Specificity Immunoglobulin G Helicobacter Infections 03 medical and health sciences 0302 clinical medicine Age groups Internal medicine medicine Immunology and Allergy Humans 030212 general & internal medicine Aged biology Helicobacter pylori business.industry Age Factors Middle Aged biology.organism_classification medicine.disease Antibodies Bacterial 3. Good health biology.protein 030211 gastroenterology & hepatology Female Microbial Immunology business Helicobacter pylori Antibody
Zdroj:	Clinical and diagnostic laboratory immunology. 11(6)
ISSN:	1071-412X
Popis:	The accuracy of Helicobacter pylori antibody assays for 561 consecutive adult outpatients who had undergone gastroscopy was studied. The sensitivity of an immunoglobulin G test was 99 to 100% for all age groups, but the specificity declined by age group, from 99% for those aged 15 to 49 years to 75% for those aged ≥65 years. The exclusion of false-positive results for patients with atrophic gastritis improved the specificity to 93 to 97% for the older age groups.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f44a35c7fd51d53d8f20f588f66fc276 https://pubmed.ncbi.nlm.nih.gov/15539526 Zobrazit plný text záznamu