| Autor: |
Vesile Elif Toy, Tamer Ataoglu, Abubekir Eltas, Husniye Gul Otlu, Aysun Bay Karabulut |
| Přispěvatelé: |
İstinye Üniversitesi, Diş Hekimliği Fakültesi, Klinik Bilimler Bölümü, Ataoglu, Tamer, AAL-2379-2021 |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Clinical Oral Investigations. |
| ISSN: |
1436-3771 |
| DOI: |
10.1007/s00784-022-04854-7 |
| Popis: |
Objectives: Adipocytokines and oxidative stress (OS) are involved in the pathogenesis of both obesity and periodontitis. The aim of this study was to evaluate periodontal therapy outcomes in terms of serum and gingival crevicular fluid (GCF) levels of adipocytokines and OS markers in obese patients with periodontitis, in order to have an insight into the association between obesity and periodontitis. Materials and Methods: A total of 39 patients (20 obese, 19 non-obese) with periodontitis were included in this study. Clinical periodontal parameters were assessed; serum and GCF levels of adipocytokines and OS markers were evaluated by ELISA at baseline and 3 months after non-surgical periodontal therapy. Results: Significant improvements in clinical periodontal parameters were observed in both groups at 3 months (pConclusions:It seems that leptin, TNF-α, and TOS contribute to systemic inflammatory and oxidative statein patients with obesity. Despite improvements in clinical periodontal parameters, obesity might be a modulating factor in the development and progression of periodontal disease in terms of some adipocytokines and OS markers. Clinical Relevance: Since the global burden of both obesity and periodontitis is continuously increasing, the management of these inflammatory diseases has become more important. The current study contributes to our understanding of the role of OS and adipocytokines on the relationship between obesity and periodontitis by response to periodontal treatment. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink