Cartilage Surgery in Overweight Patients : Clinical and MRI Results after the Autologous Matrix-Induced Chondrogenesis Procedure
| Autor: | Christoph von Schulze Pellengahr, Kiriakos Daniilidis, Wolfram Teske, Christopher Ull, Matthias Lahner, Nina Lahner, Lars Victor von Engelhardt, Marco Hagen |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Adult
Cartilage Articular Male medicine.medical_specialty Knee Joint Article Subject lcsh:Medicine Overweight Transplantation Autologous General Biochemistry Genetics and Molecular Biology Collagen Type I Lesion 03 medical and health sciences 0302 clinical medicine medicine Humans 030222 orthopedics General Immunology and Microbiology Tissue Scaffolds business.industry Cartilage lcsh:R 030229 sport sciences General Medicine Middle Aged Sport- und Bewegungswissenschaften Chondrogenesis Magnetic Resonance Imaging Surgery Autologous matrix-induced chondrogenesis medicine.anatomical_structure Knee pain Collagen Type III Orthopedic surgery Female medicine.symptom business Body mass index Cartilage Diseases Research Article |
| Zdroj: | BioMed Research International BioMed Research International, Vol 2018 (2018) |
| Popis: | Modern orthopaedic surgery provides a variety of techniques for cartilage repair. The Autologous Matrix-Induced Chondrogenesis (AMIC) procedure is a single-step technique with a collagen I/III scaffold for the treatment of full-thickness cartilage lesions. The aim of the study was to analyze the outcome of the AMIC procedure in overweight patients with knee cartilage defects. Overweight patients treated with AMIC surgery were followed up by clinical and MRI examination. 9 patients with a cartilage defect of the knee with a mean lesion size of 2.1±1.2 cm2 and an average body mass index (BMI) of 29.3 were available for the follow-up. The Lysholm Score was significantly improved by the AMIC procedure (38 to 67, p≤0.008). The VAS Score was significantly lower after the procedure (9 to 3, p≤0.018). In the postoperative MOCART Scale, the scaffold reached defect covering of 80%. However, 2 patients had to be revised due to persisting knee pain. The AMIC procedure enhances pain reduction and gain of knee function for cartilage defects of overweight patients. However, in cases of an increased BMI, the patient had to be informed that success rate is reduced despite good defect covering. |
| Databáze: | OpenAIRE |
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