Acute Toxicity of Insecticide Thiamethoxam to Crayfish (Astacus leptodactylus): Alterations in Oxidative Stress Markers, ATPases and Cholinesterase
| Autor: | Ertan Yoloğlu, Özden Barım Öz, Aysel Alkan Uçkun, Miraç Uçkun |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Antioxidant
medicine.medical_treatment Glutathione reductase Astacus leptodactylus Carboxylesterase chemistry.chemical_compound antioxidant enzymes medicine QD1-999 General Environmental Science chemistry.chemical_classification biology Glutathione peroxidase Neonicotinoid insecticide toxicity Glutathione acetylcholinesterase biology.organism_classification Acetylcholinesterase Chemistry chemistry Biochemistry General Earth and Planetary Sciences crustacean metabolic enzymes |
| Zdroj: | Acta Chimica Slovenica, Vol 68, Iss 3, Pp 521-531 (2021) |
| ISSN: | 1580-3155 1318-0207 |
| Popis: | Thiamethoxam (Thmx) is a globally used neonicotinoid pesticide contaminated in freshwater ecosystems with residues detected in fishery products. Astacus leptodactylus is a popular freshwater crustacean that is cultivated and exported in many countries. In this study, we investigated the acute toxic effects of Thmx on A. leptodactylus using various biomarkers (acetylcholinesterase, carboxylesterase, glutathione S-transferase, glutathione, superoxide dismutase, glutathione peroxidase, glutathione reductase, and adenosinetriphosphatases). The 96-h LC50 value of Thmx was calculated as 8.95 mg active ingredient L–1. As the dose of Thmx increased, oxidative stress was induced by the inhibition/activation of antioxidant enzymes, while the activities of acetylcholinesterase, carboxylesterase and adenosinetriphosphatases were inhibited. As a result, it can be said that Thmx has highly toxic effects on crayfish, therefore they are under threat in the areas where this pesticide is used. |
| Databáze: | OpenAIRE |
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