Pneumonic tularaemia: experience of 58 cases from 2000 to 2012 in Northern Finland
| Autor: | Janne Henry, Terttu Harju, Sara A. Väyrynen, Sini Lahti, Heikki Kauma, Elina Saarela |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male 0301 basic medicine Microbiology (medical) medicine.medical_specialty Pediatrics 030106 microbiology Computed tomography Northern finland Pneumonic tularaemia Mediastinoscopy 03 medical and health sciences 0302 clinical medicine Bronchoscopy Epidemiology Pneumonia Bacterial medicine Humans 030212 general & internal medicine Francisella tularensis Tularemia Finland Aged Retrospective Studies General Immunology and Microbiology medicine.diagnostic_test business.industry Incidence Incidence (epidemiology) Outbreak General Medicine Middle Aged Prognosis Anti-Bacterial Agents Surgery Intensive Care Units Infectious Diseases Immunoglobulin G Female Seasons Tomography X-Ray Computed business |
| Zdroj: | Infectious Diseases. 49:758-764 |
| ISSN: | 2374-4243 2374-4235 |
| DOI: | 10.1080/23744235.2017.1341054 |
| Popis: | Pneumonic tularaemia is less common clinical form of tularaemia compared with the ulceroglandular form, with only a limited number of case reports and case series in Europe. In Finland, Northern Ostrobothnia is an endemic area of tularaemia with occasional seasonal outbreaks.In our study, a consecutive series of 58 pneumonic tularaemia cases diagnosed and treated in Oulu University Hospital in 2000-2012 were retrospectively analysed in terms of epidemiology, clinical course, and prognosis.The incidence of pneumonic tularaemia showed peaks in cycles of a few years and most cases were diagnosed in late summer or early autumn. Respiratory symptoms were absent in 47% of patients, and 7% had normal chest X-ray. The chest computed tomography (CT) was performed in 81% of patients, demonstrating variable findings associated with pneumonic tularaemia. Bronchoscopy was performed for 22 (38%) patients and four (18%) of these also proceeded into mediastinoscopy. Moreover, thoracoscopy was performed for one (2%) patient. Two (3%) patients were treated shortly in the intensive care unit (ICU) during their stay in hospital. No mortality was observed.Most cases of pneumonic tularaemia are diagnosed during the seasonal outbreaks. The lack of specific symptoms often complicates the diagnosis and leads to unnecessarily invasive examinations. |
| Databáze: | OpenAIRE |
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