SOCS3 inhibits TPO-stimulated, but not spontaneous, megakaryocytic growth in primary myelofibrosis
| Autor: | Stéphane Giraudier, Carole Tonetti, Jean-Jacques Kiladjian, Rodolphe Besancenot, Gérard Socié, Dominique Bordessoule, Ronan Chaligne, William Vainchenker, Caroline Marty |
|---|---|
| Přispěvatelé: | Institut Gustave Roussy (IGR), Groupe Immunologie et Thérapie Génique, Université Paris-Sud - Paris 11 (UP11)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service d'Hématologie biologique [CHU Limoges], CHU Limoges, Service d'Hématologie clinique et thérapie cellulaire [CHU Limoges], Université de Limoges (UNILIM), Hematopoïèse et Cellules Souches (U362), Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire d'hématologie, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Henri Mondor-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Sud - Paris 11 (UP11) |
| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: |
endocrine system
Cancer Research Suppressor of Cytokine Signaling Proteins Biology 03 medical and health sciences fluids and secretions 0302 clinical medicine MESH: DNA Methylation MESH: Cell Proliferation MESH: Promoter Regions Genetic medicine Humans SOCS3 Myelofibrosis Promoter Regions Genetic ComputingMilieux_MISCELLANEOUS 030304 developmental biology Cell Proliferation 0303 health sciences Primary (chemistry) MESH: Humans digestive oral and skin physiology food and beverages Hematology DNA Methylation medicine.disease MESH: Thrombopoietin MESH: Suppressor of Cytokine Signaling Proteins 3. Good health MESH: Megakaryocytes Oncology Thrombopoietin Primary Myelofibrosis Suppressor of Cytokine Signaling 3 Protein 030220 oncology & carcinogenesis embryonic structures Immunology Cancer research [SDV.IMM]Life Sciences [q-bio]/Immunology MESH: Primary Myelofibrosis Megakaryocytes |
| Zdroj: | Leukemia Leukemia, 2009, 23 (6), pp.1186-90. ⟨10.1038/leu.2009.22⟩ Leukemia, Nature Publishing Group: Open Access Hybrid Model Option B, 2009, 23 (6), pp.1186-90. ⟨10.1038/leu.2009.22⟩ |
| ISSN: | 0887-6924 1476-5551 |
| DOI: | 10.1038/leu.2009.22⟩ |
| Popis: | SOCS3 inhibits TPO-stimulated, but not spontaneous, megakaryocytic growth in primary myelofibrosis |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|