RAPID DEGENERATION OF AMPULLARY ELECTRORECEPTOR ORGANS AFTER DENERVATION
| Autor: | Michael V. L. Bennett, R. Bruce Szamier |
|---|---|
| Rok vydání: | 1973 |
| Předmět: |
Time Factors
Sensory Receptor Cells Synaptic Membranes Nerve fiber Degeneration (medical) Nerve Fibers Myelinated Article Methods medicine Animals Neurons Afferent Inclusion Bodies Denervation Epidermis (botany) biology Kryptopterus Fishes Sense Organs Cell Biology Anatomy biology.organism_classification Mitochondria Cell biology Tissue Degeneration medicine.anatomical_structure Synapses biology.protein Synaptic Vesicles Extracellular Space Neurotrophin |
| Zdroj: | The Journal of Cell Biology |
| ISSN: | 1540-8140 0021-9525 |
| DOI: | 10.1083/jcb.56.2.466 |
| Popis: | Electroreceptors (ampullary organs) of the transparent catfish (Kryptopterus bicirrhus) lie in the epidermis, and contain spherical receptor cells that receive purely afferent innervation from the lateral line nerve. Section of this nerve causes rapid degenerative changes to occur in the receptors. Fine structural alterations occur in the receptor cell synapses and nerve fiber 6–12 h postoperatively. Disruption of the receptor cells begins by 18 h and most are lost by 48 h. By 72 h supporting cells and secretory cells also show marked degeneration, and by 96 h they may be totally lost. The rapid degeneration of the electroreceptor organs of Kryptopterus should make them a useful preparation for analysis of neurotrophic functions. |
| Databáze: | OpenAIRE |
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