Porous aerogel and core/shell nanoparticles for controlled drug delivery: A review
Autor: | M.C. Ibarra-Alonso, Antonia Martínez-Luévanos, Tzipatly A. Esquivel-Castro, Jorge Oliva |
---|---|
Rok vydání: | 2018 |
Předmět: |
Materials science
Chemical substance technology industry and agriculture Shell (structure) Nanoparticle Bioengineering Core (manufacturing) Aerogel 02 engineering and technology equipment and supplies 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences 0104 chemical sciences Biomaterials Chemical engineering Mechanics of Materials Delayed-Action Preparations Drug delivery Surface modification Nanoparticles 0210 nano-technology Porosity |
Zdroj: | Materials scienceengineering. C, Materials for biological applications. 96 |
ISSN: | 1873-0191 |
Popis: | This review presents the methods and general strategies for the synthesis of porous aerogels and core/shell nanoparticles with efficient and controlled drug delivery. Different mechanisms of drug delivery are also discussed, which are influenced by the porosity, surface area, pH and surface functionalization of the aerogel and core/shell nanoparticles. Various porous inorganic, organic, and hybrid systems were compared. In addition, the main physical and chemical characteristics of these porous nanoparticles which enhance the drug loading on the porous nanoparticles were discussed. |
Databáze: | OpenAIRE |
Externí odkaz: |