Intra-observer agreements in multidisciplinary team assessments of pancreatic cancer patients
Autor: | Svein Olav Bratlie, Francis P. Robertson, Stephen J. Wigmore, Giasemi Koutouzi, Robbert J. de Haas, Marielle M.E. Coolsen, Maarten W Nijkamp, Jan Persson, Jules J.G. Slangen, Claus Wilki Fristrup, Razvan L. Miclea, Ewen M Harrison, Jakob Kirkegård, Mohammed S. S. Al-Saiddi, Ole Jacob Greve, Marcel den Dulk, Frank Viborg Mortensen, Michael Bau Mortensen, Jon Arne Søreide |
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Přispěvatelé: | MUMC+: MA Heelkunde (9), RS: NUTRIM - R2 - Liver and digestive health, MUMC+: DA BV Medisch Specialisten Radiologie (9) |
Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
medicine.medical_specialty
pancreatic cancer Locally advanced Multidisciplinary team Borderline resectable Pancreatic cancer Clinical information Antineoplastic Combined Chemotherapy Protocols medicine MANAGEMENT Humans In patient TUMOR BOARD Stage (cooking) resectability Observer Variation Patient Care Team business.industry General Medicine medicine.disease Prognosis Intra observer Neoadjuvant Therapy Pancreatic Neoplasms Oncology treatment allocation Surgery Radiology variation business neoadjuvant chemotherapy |
Zdroj: | Kirkegård, J, Al-Saiddi, M, Bratlie, S O, Coolsen, M, de Haas, R J, den Dulk, M, Fristrup, C, Greve, O J, Harrison, E, Koutouzi, G, Miclea, R L, Mortensen, M B, Nijkamp, M W, Persson, J, Robertson, F P, Slangen, J J G, Søreide, J A, Wigmore, S J & Mortensen, F V 2021, ' Intra-observer agreements in multidisciplinary team assessments of pancreatic cancer patients ', Journal of Surgical Oncology . https://doi.org/10.1002/jso.26670 Journal of Surgical Oncology, 124(8), 1402-1408. Wiley Kirkegård, J, Al-Saiddi, M, Bratlie, S O, Coolsen, M, de Haas, R J, den Dulk, M, Fristrup, C W, Greve, O J, Harrison, E, Koutouzi, G, Miclea, R L, Mortensen, M B, Nijkamp, M W, Persson, J, Robertson, F P, Slangen, J J G, Søreide, J A, Wigmore, S J & Mortensen, F V 2021, ' Intra-observer agreements in multidisciplinary team assessments of pancreatic cancer patients ', Journal of Surgical Oncology, vol. 124, no. 8, pp. 1402-1408 . https://doi.org/10.1002/jso.26670 Kirkegård, J, Al-Saiddi, M, Bratlie, S O, Coolsen, M, de Haas, R J, den Dulk, M, Fristrup, C, Greve, O J, Harrison, E, Koutouzi, G, Miclea, R L, Mortensen, M B, Nijkamp, M W, Persson, J, Robertson, F P, Slangen, J J G, Søreide, J A, Wigmore, S J & Mortensen, F V 2021, ' Intra-observer agreements in multidisciplinary team assessments of pancreatic cancer patients ', Journal of Surgical Oncology, vol. 124, no. 8, pp. 1402-1408 . https://doi.org/10.1002/jso.26670 |
ISSN: | 0022-4790 |
Popis: | BACKGROUND AND METHODS: Treatment strategies for pancreatic cancer patients are made by a multidisciplinary team (MDT) board. We aimed to assess intra-observer variance at MDT boards. Participating units staged, assessed resectability, and made treatment allocations for the same patients as they did two years earlier. We disseminated clinical information and CT images of pancreatic cancer patients judged by one MDT board to have nonmetastatic pancreatic cancer to the participating units. All units were asked to re-assess the TNM stage, resectability, and treatment allocation for each patient. To assess intra-observer variance, we computed %-agreements for each participating unit, defined as low (75%) agreement.RESULTS: Eighteen patients were re-assessed by six MDT boards. The overall agreement was moderate for TNM-stage (ranging from 50%-70%) and resectability assessment (53%) but low for treatment allocation (46%). Agreement on resectability assessments was low to moderate. Findings were similar but more pronounced for treatment allocation. We observed a shift in treatment strategy towards increasing use of neoadjuvant chemotherapy, particularly in patients with borderline resectable and locally advanced tumors.CONCLUSIONS: We found substantial intra-observer agreement variations across six different MDT boards of 18 pancreatic cancer patients with two years between the first and second assessment. |
Databáze: | OpenAIRE |
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