Use of fibrin glue as a sealant at the anastomotic line in laparoscopic pyeloplasty: A randomised controlled trial
| Autor: | Mohamed Kotb, Ahmed Tawfick, Ahmed Safaan, Hassan Shaker, Ahmed Farouk, Mohamed Yassin, Alaa Abdellmaksoud |
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| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
DTPA diethylene-triamine-penta-acetic acid Urology 030232 urology & nephrology Anastomosis law.invention 03 medical and health sciences 0302 clinical medicine Randomized controlled trial law otorhinolaryngologic diseases medicine Laparoscopic pyeloplasty Stentless pyeloplasty Fibrin glue PUJ obstruction business.industry Sealant Jj stent Surgery LPP laparoscopic pyeloplasty body regions PUJO PUJ obstruction T½ clearance half-time (renogram) surgical procedures operative 030220 oncology & carcinogenesis Original Article business CONSORT Consolidated Standards of Reporting Trials |
| Zdroj: | Arab Journal of Urology |
| ISSN: | 2090-598X |
| DOI: | 10.1016/j.aju.2016.08.002 |
| Popis: | Objective To assess the effectiveness of fibrin glue as a sealant at the anastomotic line of a stentless laparoscopic pyeloplasty (LPP) repair instead of JJ stent insertion. Patients and methods In all, 46 patients with pelvi-ureteric junction obstruction scheduled for LPP were randomised into two groups each containing 23 patients. Group A underwent stented repair, while group B had a stentless repair together with sealing of the anastomotic line with fibrin glue. Results There was no statistically significant difference between the groups for the postoperative improvement in the renal scan and intravenous urography. However, there was a statistically significant decrease in early postoperative adverse events in group B. In group A, all the patients had irritative lower urinary tract symptoms (LUTS) and 16 (72.7%) had postoperative urinary tract infections (UTIs). In group B, no patient had a UTI or irritative LUTS. In all, 21 patients (95.4%) in group A had minimal terminal painful haematuria; while in group B, only one patient (4.3%) had minimal total painless haematuria. Also, patients in group B were spared the need for a second anaesthesia exposure for stent removal. Conclusion The use of fibrin glue is a valid alternative to stenting in LPP with the same excellent outcome but with markedly lower short-term postoperative adverse events. |
| Databáze: | OpenAIRE |
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