Is There a Negative Interpretation Bias in Depressed Patients? An Affective Startle Modulation Study
| Autor: | Andreas Mühlberger, Marta Andreatta, Sarah Kittel-Schneider, Thomas Polak, Ann-Christine Ehlis, Andreas J. Fallgatter, Babette Wolff, Mirjam Käse, Thomas Dresler |
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| Rok vydání: | 2013 |
| Předmět: |
Adult
Male Reflex Startle media_common.quotation_subject Emotions Humans In patient Patient group Biological Psychiatry Language media_common Depression Interpretation (philosophy) Uncertainty Ambiguity Response bias Startle reaction Startle modulation Affect Psychiatry and Mental health Neuropsychology and Physiological Psychology Case-Control Studies 150 Psychologie ddc:150 Female Arousal Psychology Startle potentiation Cognitive psychology |
| Zdroj: | Neuropsychobiology. 67:201-209 |
| ISSN: | 1423-0224 0302-282X |
| DOI: | 10.1159/000347086 |
| Popis: | Background/Aims: Scientists proposed that patients with depression favour negative interpretations when appraising ambiguity. As self-report measures seem prone to response bias, implicit measures of emotional valence should be additionally used. Methods: A total of 16 patients with depression and 19 controls underwent an acoustic imagery task comprising neutral and negative words, as well as ambiguous words that could be understood either way. Affective startle modulation and direct interrogation were used to assess implicit and explicit emotional valence, respectively. We expected a negative bias for ambiguous words in the patient group, resulting in augmented startle magnitudes and preference for negative interpretations of the ambiguous words in the interrogation. Results: Surprisingly, both groups preferred neutral interpretations and showed augmented startle magnitudes to ambiguous words. Furthermore, both groups displayed an emotional startle potentiation for negative words. Conclusion: In summary, our results do not confirm a negative interpretation bias or a blunted emotional response in patients with major depression. The mismatch between self-report and affective startle reaction to ambiguous targets might reflect defensive mobilization or attention effects. OA-Komponente aus Allianzlizenz |
| Databáze: | OpenAIRE |
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