Pramipexole Ameliorates Neurologic and Psychiatric Symptoms in a Westphal Variant of Huntington's Disease

Autor:	Josef Diez, Andreas Gruber, G. Niederwieser, Raphael M. Bonelli, Peter Költringer
Rok vydání:	2002
Předmět:	Adult Agonist Pediatrics medicine.medical_specialty Levodopa medicine.drug_class Dopamine Agents Familial periodic paralysis Hypokinesia Severity of Illness Index Dopamine agonist Central nervous system disease Benserazide Pramipexole Degenerative disease Huntington's disease Internal medicine medicine Humans Pharmacology (medical) Benzothiazoles Pharmacology Depression business.industry medicine.disease Muscle Rigidity nervous system diseases Thiazoles Huntington Disease Endocrinology Dopamine Agonists Drug Therapy Combination Female Neurology (clinical) business medicine.drug
Zdroj:	Clinical Neuropharmacology. 25:58-60
ISSN:	0362-5664
Popis:	Levodopa is recommended as a therapeutic approach for patients with the hypokinetic-rigid, Westphal variant of Huntington's disease, but no guidelines are available for the case of nonrespondence to levodopa. In this study, however, we report a 34-year-old woman with this rare variant who showed a clear-cut improvement in motor function and depressive symptoms after treatment with pramipexole, a new dopamine agonist.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3f7dd83a045977d316eb0125d287eaa https://doi.org/10.1097/00002826-200201000-00011 Zobrazit plný text záznamu