National profile and treatment outcomes of patients with extrapulmonary tuberculosis in Bénin

Autor: Christine Adjonou, Arnaud Trébucq, Sophie Azon, Séverin Anagonou, Anthony D. Harries, Gabriel Ade, Gildas Agodokpessi, Serge Ade
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Bacterial Diseases
Male
Viral Diseases
Pulmonology
National Health Programs
Pleural effusion
Antitubercular Agents
HIV Infections
Immunodeficiency Viruses
Antiretroviral Therapy
Highly Active
HIV Seropositivity
Ascites
Medicine and Health Sciences
Benin
Public and Occupational Health
Young adult
Lymph Node Tuberculosis
Multidisciplinary
biology
Coinfection
Middle Aged
Lower Respiratory Tract Infections
Infectious Diseases
Treatment Outcome
Medical Microbiology
Viral Pathogens
Medicine
Female
medicine.symptom
Research Article
Adult
medicine.medical_specialty
Tuberculosis
Science
Microbiology
Mycobacterium tuberculosis
Young Adult
Internal medicine
medicine
Humans
Microbial Pathogens
Tuberculosis
Pulmonary
Retrospective Studies
business.industry
Body Weight
Biology and Life Sciences
HIV
Retrospective cohort study
Tropical Diseases
medicine.disease
biology.organism_classification
Surgery
Respiratory Infections
business
Zdroj: PLoS ONE, Vol 9, Iss 4, p e95603 (2014)
PLoS ONE
ISSN: 1932-6203
Popis: BackgroundIn sub-Saharan Africa, there is a dearth of published literature on extrapulmonary tuberculosis (EPTB).ObjectiveTo describe demographic, diagnostic and HIV-status characteristics of patients with EPTB in Bénin, their treatment outcomes, and among those who completed their treatment in the Centre National Hospitalier de Pneumo-Phtisiologie (CNHP-P), the proportion whose bodyweight increased during treatment.Material and findingsThis was a retrospective cohort study with comparisons made between EPTB and new smear-positive pulmonary tuberculosis (NPTB) patients diagnosed in the country from January to December 2011. There were 383 EPTB patients (9% of all TB cases) with a mean age of 35 years, male/female ratio of 1.3 and important regional variation. There were significantly more females (p = 0.001), children ConclusionPatients with EPTB generally do well in Bénin, although the TB Programme would benefit through more attention to accurate diagnosis and earlier start of ART in HIV-infected patients.
Databáze: OpenAIRE
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