Molluscicidal activity of cardiac glycosides isolated from Adenium obesum
| Autor: | Omer A. Basudan, Mahmoud H. El_Komy, Ali A. Al-Zabib, Ali A. El-Gamal, Maged S. Abdel-Kader, Hamdy I. Hussein, Ali S. Al-Sarar, Yasser Abobakr |
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| Rok vydání: | 2019 |
| Předmět: |
0106 biological sciences
Molluscacides Snails Biology Body weight 01 natural sciences Median lethal dose Cardiac Glycosides Lethal Dose 50 chemistry.chemical_compound Adenium obesum medicine Animals Cardiac glycoside chemistry.chemical_classification Plant Stems Traditional medicine Plant Extracts Neriifolin Glycoside General Medicine Pesticide biology.organism_classification Apocynaceae Cardenolides 010602 entomology chemistry Insect Science Cerberin Agronomy and Crop Science 010606 plant biology & botany medicine.drug |
| Zdroj: | Pest Management Science. 75:2770-2775 |
| ISSN: | 1526-4998 1526-498X |
| DOI: | 10.1002/ps.5388 |
| Popis: | Background Terrestrial mollusks are one of most important agricultural pests worldwide. Natural phytochemicals have an extended history as a source of pesticides. This study was planned to isolate molluscicidal active compounds from the stems of Adenium obesum. Results The benzene-soluble fraction of the hydroethanolic extract displayed the most potent molluscicidal activity against Monacha obstructa among different solvent fractions with a median lethal dose (LD50 ) of 4.91 µg g-1 body weight (bw). The bioactivity-guided chemical exploration of the benzene-soluble fraction led to the isolation of two known cardiac glycosides, cerberin and neriifolin which showed significant molluscicidal activity with LD50 values of 5.39 and 4.3 µg g-1 bw, respectively. Conclusion Isolation of the cardiac glycoside neriifolin from A. obesum and the molluscicidal activity of cerberin and neriifolin against terrestrial snails are reported for the first time. © 2019 Society of Chemical Industry. |
| Databáze: | OpenAIRE |
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