Fever and antipyresis in the crayfish Cambarus bartoni

Autor:	William W. Reynolds, M. E. Casterlin
Rok vydání:	1980
Předmět:	Veterinary medicine Behavior Animal biology Physiology medicine.medical_treatment Astacoidea Ambient water Thermoregulation biology.organism_classification Crayfish Aeromonas hydrophila Aeromonas Anesthesia medicine Animals Antipyretic Cambarus Saline Research Article Acetaminophen Body Temperature Regulation medicine.drug
Zdroj:	The Journal of Physiology. 303:417-421
ISSN:	0022-3751
DOI:	10.1113/jphysiol.1980.sp013296
Popis:	1. Normothermic Cambarus bartoni crayfish thermoregulating behaviourally in an electronic shuttlebox prefer a mean temperature of 22.1 degrees C +/- 0.5 S.E. of mean. 2. Injection of 1% saline, or addition of paracetamol to the ambient water, caused a statistically insignificant decrease in preferred temperature of 0.4 degrees C. 3. Injection of killed Aeromonas hydrophila bacteria into the abdomen caused a significant mean increase in preferred temperature of 1.8 degrees C (defined as a behavioural fever). 4. Injection of A. hydrophila, with paracetamol in the water, resulted in an insignificant increase of 0.1 degrees C above the normothermic temperature; thus paracetamol is antipyretic in crayfish, preventing fever but not altering afebrile thermoregulation. 5. These results suggest that similar mechanisms may be operating in the neuropharmacological mediation of fever in vertebrates and invertebrates.
Databáze:	OpenAIRE
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