Risk Factors on the Progression to Clinical Outcomes of COVID-19 Patients in South Korea: Using National Data
Autor: | Seon-Rye Kim, Yu-Rin Kim, Seoul-Hee Nam |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
medicine.medical_specialty
Health Toxicology and Mutagenesis blood variables lcsh:Medicine severity Comorbidity Article 03 medical and health sciences 0302 clinical medicine Sex Factors Risk Factors Internal medicine Republic of Korea medicine Sore throat Dementia Humans 030212 general & internal medicine Risk factor 030304 developmental biology Retrospective Studies 0303 health sciences COPD business.industry lcsh:R Public Health Environmental and Occupational Health Age Factors COVID-19 medicine.disease Hospitalization risk factor ICU Disease Progression medicine.symptom business Body mass index Abnormal Lymphocyte Kidney disease |
Zdroj: | International Journal of Environmental Research and Public Health Volume 17 Issue 23 International Journal of Environmental Research and Public Health, Vol 17, Iss 8847, p 8847 (2020) |
ISSN: | 1660-4601 |
DOI: | 10.3390/ijerph17238847 |
Popis: | 10&ndash 20% of COVID (Corona Virus Disease)-19 cases proceed to a severe stage, and age and the presence of comorbidity increased the risk of death from COVID-19. The identification of risk factors on progression to the severity stages is essential in providing more efficient and suitable management to COVID-19 patients. However, there is insufficient study on risk factors for severity stages of COVID-19 patients. In this study, 2959 confirmed COVID-19 patients were analyzed while using national data, COVID-19 patients Clinical Epidemiological Information provided from the Korea Disease Control and Prevention Agency. The epidemiological variable, hospital room, periods from confirmation to release, initial symptom and vital signs, underlying comorbidities, and initial blood variables were used to verify the relation with progression to severity stages of COVID-19 and severe COVID-19. The chi-square test, welch test, multiple regression and logistic regression analysis were performed. The ICU (Intensive Care Unit) admission rate of patients having characteristics, such as older age, male, abnormal BMI (Body Mass Index), high heart rate, high body temperature, fever, cough, sputum, sore throat, rhinorrhea, fatigue, dyspnea, change of consciousness, diabetes mellitus, hypertension, chronic artery disease, chronic kidney disease, cancer, dementia, abnormal hemoglobin, abnormal hematocrit, abnormal lymphocyte, abnormal platelets, and abnormal white blood cell were high. The risk factors for severe COVID-19 were older age, shorter hospitalization, abnormal lymphocyte, abnormal platelets, dyspnea, change of consciousness, and dementia. Whereas, significant predictors for progression to severity stages of COVID-19 were older age, longer period from confirmation to release, higher BMI, higher body temperature, abnormal lymphocyte, abnormal platelets, fever, no sore throat, dyspnea, no headache, COPD (Chronic Obstructive Pulmonary Disease), and dementia. Therefore, classifying patients with a high risk of severe stage of COVID-19 and managing patients by considering the risk factors could be helpful in the efficient management of COVID-19 patients. |
Databáze: | OpenAIRE |
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