Bioaccumulation, release and genotoxicity of stainless steel particles in marine bivalve molluscs
| Autor: | Emily L. Vernon, Awadhesh N. Jha, Maria F. Ferreira, Danielle L. Slomberg, Veronique Malard, Christian Grisolia, Mickaël Payet, Andrew Turner |
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| Přispěvatelé: | Plymouth University, Centre européen de recherche et d'enseignement des géosciences de l'environnement (CEREGE), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Collège de France (CdF (institution))-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Interactions Protéine Métal (IPM), Institut de Biosciences et Biotechnologies d'Aix-Marseille (ex-IBEB) (BIAM), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Institut de Recherche sur la Fusion par confinement Magnétique (IRFM), Commissariat à l'énergie atomique et aux énergies alternatives (CEA) |
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
Mytilus
Environmental Engineering l Nuclear energy Health Toxicology and Mutagenesis fungi Bivalve Public Health Environmental and Occupational Health technology industry and agriculture General Medicine General Chemistry Stainless Steel Pollution Bioaccumulation Stainless stee Animals Environmental Chemistry DNA damage Comet Assay [SDV.TOX.ECO]Life Sciences [q-bio]/Toxicology/Ecotoxicology Genotoxicity [SDE.BE]Environmental Sciences/Biodiversity and Ecology |
| Zdroj: | Chemosphere Chemosphere, 2022, 303, Part 2, pp.134914. ⟨10.1016/j.chemosphere.2022.134914⟩ |
| ISSN: | 0045-6535 |
| DOI: | 10.1016/j.chemosphere.2022.134914⟩ |
| Popis: | International audience; During the decommissioning and removal of radioactive material in nuclear facilities, fine, tritiated dusts of stainless steel, cement or tungsten are generated that could be accidently released to the environment. However, the potential radio- and ecotoxicological effects these tritiated particles may have are unknown. In this study, stainless steel particles (SSPs) representative of those likely to be tritiated are manufactured by hydrogenation and their tissue-specific bioaccumulation, release (depuration) and subsequent genotoxic response have been studied in the marine mussel, Mytilus galloprovincialis, as a baseline for future assessments of the potential effects of tritiated SSPs. Exposure to 1000 μg L−1 of SSPs and adopting Cr as a proxy for stainless steel revealed relatively rapid accumulation (∼5 h) in the various mussel tissues but mostly in the digestive gland. Over longer periods up to 18 days, SSPs were readily rejected and egested as faecal material. DNA strand breaks, as a measure of genotoxicity, were determined at each time point in mussel haemocytes using single cell gel electrophoresis, or the comet assay. Lack of chemical genotoxicity was attributed to the rapid processing of SSP particles and limited dissolution of elemental components of steel. Further work employing tritiated SSPs will enable radio-toxicology to be studied without the confounding effects of chemical toxicity |
| Databáze: | OpenAIRE |
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