Left ventricular pseudoaneurysm associated with systemic lupus erythematosus

Autor:	L M M F Demarchi, Luciana Parente Costa Seguro, Clarissa de Queiroz Pimentel, Eloisa Bonfa, B L R Faillace, Leonardo Santos Hoff, C E Rochitte
Rok vydání:	2019
Předmět:	Adult medicine.medical_specialty Heart Ventricles Infarction 030204 cardiovascular system & hematology Coronary Angiography Chest pain 03 medical and health sciences Pseudoaneurysm Pericarditis 0302 clinical medicine Rheumatology immune system diseases Antiphospholipid syndrome Cardiac magnetic resonance imaging Internal medicine Animals Humans Lupus Erythematosus Systemic Medicine Pericardium cardiovascular diseases Heart Aneurysm skin and connective tissue diseases Heart Failure 030203 arthritis & rheumatology medicine.diagnostic_test business.industry medicine.disease Magnetic Resonance Imaging medicine.anatomical_structure Heart failure cardiovascular system Cardiology Cattle Female Radiography Thoracic medicine.symptom business Aneurysm False
Zdroj:	Lupus. 28:681-684
ISSN:	1477-0962 0961-2033
DOI:	10.1177/0961203319837359
Popis:	Systemic lupus erythematosus (SLE) is associated with several cardiac manifestations but, to our knowledge, there have been no previously published reports on left ventricular (LV) pseudoaneurysm in this disease. We describe a case of a 30-year-old woman with SLE who presented with a disease flare (acute and subacute cutaneous lupus, pericarditis, fever, leukopenia) associated with heart failure syndrome. The patient was diagnosed with a large LV pseudoaneurysm and a bovine pericardium patch closure was performed. Coronary arteries were angiographically normal, and cardiac magnetic resonance imaging did not exhibit detectable myocardial fibrosis or infarction. Trauma, previous cardiac surgery, Chagas disease, and antiphospholipid syndrome were excluded. Histopathology of the pericardium revealed lymphocytic arteriolitis raising the possibility of an autoimmune-mediated mechanism for this complication. The unequivocal concomitant diagnosis of lupus flare, the exclusion of other causes of pseudoaneurysm and the histopathological finding of arteriolitis in this patient reinforces the hypothesis of lupus-mediated lesion.
Databáze:	OpenAIRE
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